TY - JOUR
T1 - Rapid suppression of Onchocerca volvulus transmission in two communities of the Southern Chiapas focus, Mexico, achieved by quarterly treatments with Mectizan
AU - Rodríguez-Pérez, Mario A.
AU - Lutzow-Steiner, Miguel A.
AU - Segura-Cabrera, Aldo
AU - Lizarazo-Ortega, Cristian
AU - Domínguez-Vázquez, Alfredo
AU - Sauerbrey, Mauricio
AU - Richards, Frank
AU - Unnasch, Thomas R.
AU - Hassan, Hassan K.
AU - Hernández-Hernández, Raymundo
PY - 2008/8
Y1 - 2008/8
N2 - The impact of quarterly Mectizan (ivermectin) treatments on transmission, microfiladermia, and ocular lesions was evaluated in two formerly hyperendemic communities (Las Golondrinas and Las Nubes II) located in the main endemic focus for onchocerciasis in Southern Chiapas, Mexico. The data suggest that Onchocerca volvulus transmission has been suppressed after elimination of microfiladermia in these two communities. Increasing the frequency of Mectizan treatment to four times per year appears to have resulted in the rapid suppression of transmission in communities with residual transmission.
AB - The impact of quarterly Mectizan (ivermectin) treatments on transmission, microfiladermia, and ocular lesions was evaluated in two formerly hyperendemic communities (Las Golondrinas and Las Nubes II) located in the main endemic focus for onchocerciasis in Southern Chiapas, Mexico. The data suggest that Onchocerca volvulus transmission has been suppressed after elimination of microfiladermia in these two communities. Increasing the frequency of Mectizan treatment to four times per year appears to have resulted in the rapid suppression of transmission in communities with residual transmission.
UR - http://www.scopus.com/inward/record.url?scp=49449087482&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2008.79.239
DO - 10.4269/ajtmh.2008.79.239
M3 - Artículo
SN - 0002-9637
VL - 79
SP - 239
EP - 244
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 2
ER -