Rapid suppression of Onchocerca volvulus transmission in two communities of the Southern Chiapas focus, Mexico, achieved by quarterly treatments with Mectizan

Mario A. Rodríguez-Pérez, Miguel A. Lutzow-Steiner, Aldo Segura-Cabrera, Cristian Lizarazo-Ortega, Alfredo Domínguez-Vázquez, Mauricio Sauerbrey, Frank Richards, Thomas R. Unnasch, Hassan K. Hassan, Raymundo Hernández-Hernández

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27 Scopus citations

Abstract

The impact of quarterly Mectizan (ivermectin) treatments on transmission, microfiladermia, and ocular lesions was evaluated in two formerly hyperendemic communities (Las Golondrinas and Las Nubes II) located in the main endemic focus for onchocerciasis in Southern Chiapas, Mexico. The data suggest that Onchocerca volvulus transmission has been suppressed after elimination of microfiladermia in these two communities. Increasing the frequency of Mectizan treatment to four times per year appears to have resulted in the rapid suppression of transmission in communities with residual transmission.

Original languageEnglish
Pages (from-to)239-244
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume79
Issue number2
DOIs
StatePublished - Aug 2008

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