Quinoid systems in chemistry and pharmacology

Julio López; Fabiola De La Cruz; Yolanda Alcaraz; Francisco Delgado; Miguel A. Vázquez

doi:10.1007/s00044-015-1412-y

Quinoid systems in chemistry and pharmacology

Julio López, Fabiola De La Cruz, Yolanda Alcaraz, Francisco Delgado, Miguel A. Vázquez

Escuela Nacional de Ciencias Biológicas (ENCB)

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

23 Citas (Scopus)

Resumen

In this paper, we present a brief review of quinoid systems, focusing on their chemical synthesis over the last decade. We address not only major methods of synthesizing quinoids, but also their involvement in biological processes. We highlight their medical relevance and versatility, including antitumor, antiretroviral, or antihypertensive agents, properties determined by their various patterns of substitution. Graphical Abstract: [Figure not available: see fulltext.]

Idioma original	Inglés
Páginas (desde-hasta)	3599-3620
Número de páginas	22
Publicación	Medicinal Chemistry Research
Volumen	24
N.º	10
DOI	https://doi.org/10.1007/s00044-015-1412-y
Estado	Publicada - 31 oct. 2015

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abstract = "In this paper, we present a brief review of quinoid systems, focusing on their chemical synthesis over the last decade. We address not only major methods of synthesizing quinoids, but also their involvement in biological processes. We highlight their medical relevance and versatility, including antitumor, antiretroviral, or antihypertensive agents, properties determined by their various patterns of substitution. Graphical Abstract: [Figure not available: see fulltext.]",

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T1 - Quinoid systems in chemistry and pharmacology

AU - López, Julio

AU - De La Cruz, Fabiola

AU - Alcaraz, Yolanda

AU - Delgado, Francisco

AU - Vázquez, Miguel A.

PY - 2015/10/31

Y1 - 2015/10/31

N2 - In this paper, we present a brief review of quinoid systems, focusing on their chemical synthesis over the last decade. We address not only major methods of synthesizing quinoids, but also their involvement in biological processes. We highlight their medical relevance and versatility, including antitumor, antiretroviral, or antihypertensive agents, properties determined by their various patterns of substitution. Graphical Abstract: [Figure not available: see fulltext.]

AB - In this paper, we present a brief review of quinoid systems, focusing on their chemical synthesis over the last decade. We address not only major methods of synthesizing quinoids, but also their involvement in biological processes. We highlight their medical relevance and versatility, including antitumor, antiretroviral, or antihypertensive agents, properties determined by their various patterns of substitution. Graphical Abstract: [Figure not available: see fulltext.]

KW - Cytotoxicity

KW - Natural products

KW - Pharmacology

KW - Quinone

KW - Redox

KW - Synthesis

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U2 - 10.1007/s00044-015-1412-y

DO - 10.1007/s00044-015-1412-y

M3 - Artículo de revisión

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SP - 3599

EP - 3620

JO - Medicinal Chemistry Research

JF - Medicinal Chemistry Research

IS - 10

ER -

Quinoid systems in chemistry and pharmacology

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