TY - JOUR
T1 - Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications
T2 - Focus on nanomedicine in cancer
AU - Espinoza, Sergio Miguel
AU - Patil, Harshal Indrabhan
AU - San Martin Martinez, Eduardo
AU - Casañas Pimentel, Rocio
AU - Ige, Pradum Pundlikrao
N1 - Publisher Copyright:
© 2019, © 2019 Taylor & Francis Group, LLC.
PY - 2020/1/22
Y1 - 2020/1/22
N2 - Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.
AB - Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.
KW - Nanomedicine
KW - cancer
KW - drug delivery systems
KW - poly-ε-caprolactone
KW - polymeric nanostructures
UR - http://www.scopus.com/inward/record.url?scp=85072637108&partnerID=8YFLogxK
U2 - 10.1080/00914037.2018.1539990
DO - 10.1080/00914037.2018.1539990
M3 - Artículo
SN - 0091-4037
VL - 69
SP - 85
EP - 126
JO - International Journal of Polymeric Materials and Polymeric Biomaterials
JF - International Journal of Polymeric Materials and Polymeric Biomaterials
IS - 2
ER -