Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

Sergio Miguel Espinoza; Harshal Indrabhan Patil; Eduardo San Martin Martinez; Rocio Casañas Pimentel; Pradum Pundlikrao Ige

doi:10.1080/00914037.2018.1539990

Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

Sergio Miguel Espinoza, Harshal Indrabhan Patil, Eduardo San Martin Martinez, Rocio Casañas Pimentel, Pradum Pundlikrao Ige

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.

Original language	English
Pages (from-to)	85-126
Number of pages	42
Journal	International Journal of Polymeric Materials and Polymeric Biomaterials
Volume	69
Issue number	2
DOIs	https://doi.org/10.1080/00914037.2018.1539990
State	Published - 22 Jan 2020
Externally published	Yes

Keywords

Nanomedicine
cancer
drug delivery systems
poly-ε-caprolactone
polymeric nanostructures

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00914037.2018.1539990

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title = "Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer",

abstract = "Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.",

keywords = "Nanomedicine, cancer, drug delivery systems, poly-ε-caprolactone, polymeric nanostructures",

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doi = "10.1080/00914037.2018.1539990",

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Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer. / Espinoza, Sergio Miguel; Patil, Harshal Indrabhan; San Martin Martinez, Eduardo et al.
In: International Journal of Polymeric Materials and Polymeric Biomaterials, Vol. 69, No. 2, 22.01.2020, p. 85-126.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications

T2 - Focus on nanomedicine in cancer

AU - Espinoza, Sergio Miguel

AU - Patil, Harshal Indrabhan

AU - San Martin Martinez, Eduardo

AU - Casañas Pimentel, Rocio

AU - Ige, Pradum Pundlikrao

PY - 2020/1/22

Y1 - 2020/1/22

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AB - Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past few years. It is widely explored in drug delivery, where the development of nanomedicines for cancer, one of the major public health concerns nowadays, has not been the exception. As a biocompatible, biodegradable and bioresorbable polymer, PCL has also found plenty of uses in the form of microparticles and scaffolds; so is the main objective of the present review to emphasize its potential and present its properties along with applications in the pharmaceutical and biomedical area with a special focus on nanomedicine in cancer.

KW - Nanomedicine

KW - cancer

KW - drug delivery systems

KW - poly-ε-caprolactone

KW - polymeric nanostructures

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DO - 10.1080/00914037.2018.1539990

M3 - Artículo

SN - 0091-4037

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SP - 85

EP - 126

JO - International Journal of Polymeric Materials and Polymeric Biomaterials

JF - International Journal of Polymeric Materials and Polymeric Biomaterials

IS - 2

ER -

Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

Abstract

Keywords

UN SDGs

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