Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

Preetismita Borah; Gongutri Borah; Arabinda C. Nath; Wajid Latif; Bimal Krishna Banik

doi:10.1002/slct.202203758

Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

Preetismita Borah, Gongutri Borah, Arabinda C. Nath, Wajid Latif, Bimal Krishna Banik

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

5 Citas (Scopus)

Resumen

The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.

Idioma original	Inglés
Número de artículo	e202203758
Publicación	ChemistrySelect
Volumen	8
N.º	4
DOI	https://doi.org/10.1002/slct.202203758
Estado	Publicada - 27 ene. 2023
Publicado de forma externa	Sí

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abstract = "The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.",

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AU - Borah, Preetismita

AU - Borah, Gongutri

AU - Nath, Arabinda C.

AU - Latif, Wajid

AU - Banik, Bimal Krishna

PY - 2023/1/27

Y1 - 2023/1/27

N2 - The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.

AB - The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.

KW - Anti-malarial

KW - Anticancer

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KW - Mannich Reaction

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Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

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