Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

Preetismita Borah; Gongutri Borah; Arabinda C. Nath; Wajid Latif; Bimal Krishna Banik

doi:10.1002/slct.202203758

Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

Preetismita Borah, Gongutri Borah, Arabinda C. Nath, Wajid Latif, Bimal Krishna Banik

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.

Original language	English
Article number	e202203758
Journal	ChemistrySelect
Volume	8
Issue number	4
DOIs	https://doi.org/10.1002/slct.202203758
State	Published - 27 Jan 2023
Externally published	Yes

Keywords

Anti-malarial
Anticancer
Asymmetric
Mannich Reaction
Multicomponent

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10.1002/slct.202203758

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AU - Banik, Bimal Krishna

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AB - The Mannich reaction is one of the most broadly used organic reactions for constructing C−N and C−C bonds in synthetic chemistry. This review focuses on the multicomponent Mannich reaction and its variants for the synthesis of biologically active moieties such as anticancer, antimicrobial, antimalarial, antitubercular, anti-inflammatory and anticonvulsant molecules. A few organocatalyzed asymmetric Mannich reactions are also incorporated.

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KW - Anticancer

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Facile Multicomponent Mannich Reaction towards Biologically Active Compounds

Abstract

Keywords

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