erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

Alma V. Vargas-Valencia; Virginia Sánchez-Monroy; Nadia M. Pérez-Vielma; Jaime López-Cruz; Jesús G. Silva-Escobedo; Lidia F. Huerta-Nuñez; Silverio Soto-Alvarez; César A. González-Díaz

doi:10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

Alma V. Vargas-Valencia, Virginia Sánchez-Monroy, Nadia M. Pérez-Vielma, Jaime López-Cruz, Jesús G. Silva-Escobedo, Lidia F. Huerta-Nuñez, Silverio Soto-Alvarez, César A. González-Díaz

Producción científica: Capítulo del libro/informe/acta de congreso › Contribución a la conferencia › revisión exhaustiva

Resumen

Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

Idioma original	Inglés
Título de la publicación alojada	VI Latin American Congress on Biomedical Engineering, CLAIB 2014
Editores	Ariel Braidot, Alejandro Hadad
Editorial	Springer Verlag
Páginas	687-690
Número de páginas	4
ISBN (versión digital)	9783319131160
DOI	https://doi.org/10.1007/978-3-319-13117-7_175
Estado	Publicada - 2015
Evento	6th Latin American Congress on Biomedical Engineering, CLAIB 2014 - Paraná, Argentina Duración: 29 oct. 2014 → 31 oct. 2014

Serie de la publicación

Nombre	IFMBE Proceedings
Volumen	49
ISSN (versión impresa)	1680-0737

Conferencia

Conferencia	6th Latin American Congress on Biomedical Engineering, CLAIB 2014
País/Territorio	Argentina
Ciudad	Paraná
Período	29/10/14 → 31/10/14

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10.1007/978-3-319-13117-7_175

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Vargas-Valencia, A. V., Sánchez-Monroy, V., Pérez-Vielma, N. M., López-Cruz, J., Silva-Escobedo, J. G., Huerta-Nuñez, L. F., Soto-Alvarez, S., & González-Díaz, C. A. (2015). erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. En A. Braidot, & A. Hadad (Eds.), VI Latin American Congress on Biomedical Engineering, CLAIB 2014 (pp. 687-690). (IFMBE Proceedings; Vol. 49). Springer Verlag. https://doi.org/10.1007/978-3-319-13117-7_175

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title = "erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes{\textquoteright}s experimental receptors",

abstract = "Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.",

keywords = "Nanoprobe, RT Q-PCR, Relative expression",

author = "Vargas-Valencia, {Alma V.} and Virginia S{\'a}nchez-Monroy and P{\'e}rez-Vielma, {Nadia M.} and Jaime L{\'o}pez-Cruz and Silva-Escobedo, {Jes{\'u}s G.} and Huerta-Nu{\~n}ez, {Lidia F.} and Silverio Soto-Alvarez and Gonz{\'a}lez-D{\'i}az, {C{\'e}sar A.}",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.; 6th Latin American Congress on Biomedical Engineering, CLAIB 2014 ; Conference date: 29-10-2014 Through 31-10-2014",

year = "2015",

doi = "10.1007/978-3-319-13117-7_175",

language = "Ingl{\'e}s",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

pages = "687--690",

editor = "Ariel Braidot and Alejandro Hadad",

booktitle = "VI Latin American Congress on Biomedical Engineering, CLAIB 2014",

address = "Alemania",

}

Vargas-Valencia, AV, Sánchez-Monroy, V , Pérez-Vielma, NM, López-Cruz, J, Silva-Escobedo, JG, Huerta-Nuñez, LF, Soto-Alvarez, S & González-Díaz, CA 2015, erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. En A Braidot & A Hadad (eds.), VI Latin American Congress on Biomedical Engineering, CLAIB 2014. IFMBE Proceedings, vol. 49, Springer Verlag, pp. 687-690, 6th Latin American Congress on Biomedical Engineering, CLAIB 2014, Paraná, Argentina, 29/10/14. https://doi.org/10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. / Vargas-Valencia, Alma V.; Sánchez-Monroy, Virginia ; Pérez-Vielma, Nadia M. et al.
VI Latin American Congress on Biomedical Engineering, CLAIB 2014. ed. / Ariel Braidot; Alejandro Hadad. Springer Verlag, 2015. p. 687-690 (IFMBE Proceedings; Vol. 49).

Producción científica: Capítulo del libro/informe/acta de congreso › Contribución a la conferencia › revisión exhaustiva

TY - GEN

T1 - erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

AU - Vargas-Valencia, Alma V.

AU - Sánchez-Monroy, Virginia

AU - Pérez-Vielma, Nadia M.

AU - López-Cruz, Jaime

AU - Silva-Escobedo, Jesús G.

AU - Huerta-Nuñez, Lidia F.

AU - Soto-Alvarez, Silverio

AU - González-Díaz, César A.

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2015.

PY - 2015

Y1 - 2015

N2 - Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

AB - Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

KW - Nanoprobe

KW - RT Q-PCR

KW - Relative expression

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AN - SCOPUS:84925275618

T3 - IFMBE Proceedings

SP - 687

EP - 690

BT - VI Latin American Congress on Biomedical Engineering, CLAIB 2014

A2 - Braidot, Ariel

A2 - Hadad, Alejandro

PB - Springer Verlag

T2 - 6th Latin American Congress on Biomedical Engineering, CLAIB 2014

Y2 - 29 October 2014 through 31 October 2014

ER -

Vargas-Valencia AV, Sánchez-Monroy V , Pérez-Vielma NM, López-Cruz J, Silva-Escobedo JG, Huerta-Nuñez LF et al. erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. En Braidot A, Hadad A, editores, VI Latin American Congress on Biomedical Engineering, CLAIB 2014. Springer Verlag. 2015. p. 687-690. (IFMBE Proceedings). doi: 10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

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