erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

Alma V. Vargas-Valencia; Virginia Sánchez-Monroy; Nadia M. Pérez-Vielma; Jaime López-Cruz; Jesús G. Silva-Escobedo; Lidia F. Huerta-Nuñez; Silverio Soto-Alvarez; César A. González-Díaz

doi:10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

Alma V. Vargas-Valencia, Virginia Sánchez-Monroy, Nadia M. Pérez-Vielma, Jaime López-Cruz, Jesús G. Silva-Escobedo, Lidia F. Huerta-Nuñez, Silverio Soto-Alvarez, César A. González-Díaz

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

Original language	English
Title of host publication	VI Latin American Congress on Biomedical Engineering, CLAIB 2014
Editors	Ariel Braidot, Alejandro Hadad
Publisher	Springer Verlag
Pages	687-690
Number of pages	4
ISBN (Electronic)	9783319131160
DOIs	https://doi.org/10.1007/978-3-319-13117-7_175
State	Published - 2015
Event	6th Latin American Congress on Biomedical Engineering, CLAIB 2014 - Paraná, Argentina Duration: 29 Oct 2014 → 31 Oct 2014

Publication series

Name	IFMBE Proceedings
Volume	49
ISSN (Print)	1680-0737

Conference

Conference	6th Latin American Congress on Biomedical Engineering, CLAIB 2014
Country/Territory	Argentina
City	Paraná
Period	29/10/14 → 31/10/14

Keywords

Nanoprobe
RT Q-PCR
Relative expression

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/978-3-319-13117-7_175

Cite this

Vargas-Valencia, A. V., Sánchez-Monroy, V., Pérez-Vielma, N. M., López-Cruz, J., Silva-Escobedo, J. G., Huerta-Nuñez, L. F., Soto-Alvarez, S., & González-Díaz, C. A. (2015). erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. In A. Braidot, & A. Hadad (Eds.), VI Latin American Congress on Biomedical Engineering, CLAIB 2014 (pp. 687-690). (IFMBE Proceedings; Vol. 49). Springer Verlag. https://doi.org/10.1007/978-3-319-13117-7_175

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title = "erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes{\textquoteright}s experimental receptors",

abstract = "Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.",

keywords = "Nanoprobe, RT Q-PCR, Relative expression",

author = "Vargas-Valencia, {Alma V.} and Virginia S{\'a}nchez-Monroy and P{\'e}rez-Vielma, {Nadia M.} and Jaime L{\'o}pez-Cruz and Silva-Escobedo, {Jes{\'u}s G.} and Huerta-Nu{\~n}ez, {Lidia F.} and Silverio Soto-Alvarez and Gonz{\'a}lez-D{\'i}az, {C{\'e}sar A.}",

note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.; 6th Latin American Congress on Biomedical Engineering, CLAIB 2014 ; Conference date: 29-10-2014 Through 31-10-2014",

year = "2015",

doi = "10.1007/978-3-319-13117-7_175",

language = "Ingl{\'e}s",

series = "IFMBE Proceedings",

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pages = "687--690",

editor = "Ariel Braidot and Alejandro Hadad",

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Vargas-Valencia, AV, Sánchez-Monroy, V , Pérez-Vielma, NM, López-Cruz, J, Silva-Escobedo, JG, Huerta-Nuñez, LF, Soto-Alvarez, S & González-Díaz, CA 2015, erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. in A Braidot & A Hadad (eds), VI Latin American Congress on Biomedical Engineering, CLAIB 2014. IFMBE Proceedings, vol. 49, Springer Verlag, pp. 687-690, 6th Latin American Congress on Biomedical Engineering, CLAIB 2014, Paraná, Argentina, 29/10/14. https://doi.org/10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. / Vargas-Valencia, Alma V.; Sánchez-Monroy, Virginia ; Pérez-Vielma, Nadia M. et al.
VI Latin American Congress on Biomedical Engineering, CLAIB 2014. ed. / Ariel Braidot; Alejandro Hadad. Springer Verlag, 2015. p. 687-690 (IFMBE Proceedings; Vol. 49).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

AU - Vargas-Valencia, Alma V.

AU - Sánchez-Monroy, Virginia

AU - Pérez-Vielma, Nadia M.

AU - López-Cruz, Jaime

AU - Silva-Escobedo, Jesús G.

AU - Huerta-Nuñez, Lidia F.

AU - Soto-Alvarez, Silverio

AU - González-Díaz, César A.

N1 - Publisher Copyright: © Springer International Publishing Switzerland 2015.

PY - 2015

Y1 - 2015

N2 - Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

AB - Breast cancer is the most frequent neoplasia in women worldwide. Our research group has proposed a new technology focused on the selective ablation of breast tumors by Radiofrequency (RF) assisted with Magnetic Nanoprobes. The Nanoprobes require specific antigens overexpressed in breast cancer as potential targets. The aim of this study was to evaluate the relative expression of genes erbB-3 and tgfb1 by RT Q-PCR in breast cancer tissue from an animal model as potential Nanoprobe targets. Cancer tissue was evaluated in early and late stages in order to identify a differentiated relative expression that may be used as therapeutic targets for the nanoprobe. The findings indicate that protein Tgfb1 represents a potential target for the nanoprobe in early stages of breast cancer.

KW - Nanoprobe

KW - RT Q-PCR

KW - Relative expression

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DO - 10.1007/978-3-319-13117-7_175

M3 - Contribución a la conferencia

AN - SCOPUS:84925275618

T3 - IFMBE Proceedings

SP - 687

EP - 690

BT - VI Latin American Congress on Biomedical Engineering, CLAIB 2014

A2 - Braidot, Ariel

A2 - Hadad, Alejandro

PB - Springer Verlag

T2 - 6th Latin American Congress on Biomedical Engineering, CLAIB 2014

Y2 - 29 October 2014 through 31 October 2014

ER -

Vargas-Valencia AV, Sánchez-Monroy V , Pérez-Vielma NM, López-Cruz J, Silva-Escobedo JG, Huerta-Nuñez LF et al. erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors. In Braidot A, Hadad A, editors, VI Latin American Congress on Biomedical Engineering, CLAIB 2014. Springer Verlag. 2015. p. 687-690. (IFMBE Proceedings). doi: 10.1007/978-3-319-13117-7_175

erbb-3 y tgfb1 expression in induced mammary tumors in rats as magnetic nanoprobes’s experimental receptors

Abstract

Publication series

Conference

Keywords

UN SDGs

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