Resumen
The copper(I)-induced synthesis of 1,2,3-triazoles using azides and alkynes (click chemistry) has become extremely significant. Click chemistry has been used in all aspects of drug discovery research. The product triazole serves as a linker as it readily combines with targets through hydrogen-bonding and dipole interaction. This review summarizes the application of click chemistry and triazoles as anticancer drugs. These types of reactions proceed with high selectivity, specificity, and yields. A variety of complex molecules are synthesized by this method.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 229-266 |
Número de páginas | 38 |
Publicación | Heterocycles |
Volumen | 104 |
N.º | 2 |
DOI | |
Estado | Publicada - 2022 |
Publicado de forma externa | Sí |