Resumen
The ethanol extract of the plant Hippocratea excelsa was examined for its anti-inflammatory effects using several animal models. It produced significant inhibition of carrageenan-induced paw edema and reduced the weight of cotton pellet-induced granuloma at doses of 25-100 mg/kg. The extract was found to exert a protective effect on heat-induced erythrocyte lysis at concentrations of 25, 50 and 100 μg/ml. In chronic models of formaldehyde and adjuvant arthritis, its anti-arthritic activity was found to be less than that of phenylbutazone (PNB). It may be inferred that the ethanol extract is effective against both exudative-proliferative and chronic phases of inflammation.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 85-90 |
Número de páginas | 6 |
Publicación | Journal of Ethnopharmacology |
Volumen | 47 |
N.º | 2 |
DOI | |
Estado | Publicada - 7 jul. 1995 |
Publicado de forma externa | Sí |