Resumen
Forty unrelated Mexican patients with Duchenne/Becker muscular dystrophy were analyzed for intragenic DMD gene deletions, using the multiplex amplification of 15 deletion-prone exons described by Chamberlain et al. and Beggs et al. The percentage of deletions was 52.5%, and the majority of them (86.3%) were located at the hot spot deletion region which encompasses exons 44 - 55. This frequency is higher than that found in American and European populations. There were no correlations between deletion size, location and clinical severity.
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 1-6 |
Número de páginas | 6 |
Publicación | Archives of Medical Research |
Volumen | 24 |
N.º | 1 |
Estado | Publicada - 1993 |
Publicado de forma externa | Sí |