Abstract
Forty unrelated Mexican patients with Duchenne/Becker muscular dystrophy were analyzed for intragenic DMD gene deletions, using the multiplex amplification of 15 deletion-prone exons described by Chamberlain et al. and Beggs et al. The percentage of deletions was 52.5%, and the majority of them (86.3%) were located at the hot spot deletion region which encompasses exons 44 - 55. This frequency is higher than that found in American and European populations. There were no correlations between deletion size, location and clinical severity.
Original language | English |
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Pages (from-to) | 1-6 |
Number of pages | 6 |
Journal | Archives of Medical Research |
Volume | 24 |
Issue number | 1 |
State | Published - 1993 |
Externally published | Yes |