TY - JOUR
T1 - Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population
AU - Herrera-Romano, Lisbeth
AU - Fernández-Tamayo, Nora
AU - Gómez-Conde, Eduardo
AU - Reyes-Cardoso, Juan M.
AU - Ortiz-Gutierrez, Felipe
AU - Ceballos, Guillermo
AU - Valdivia, Alejandra
AU - Piña, Patricia
AU - Salcedo, Mauricio
N1 - Funding Information:
Acknowledgments This work was partially supported by grants 69,719 and 87,244 from Fondos Sectoriales from Consejo Nacional de Ciencia y Tecnología (CONACyT-México) and IMSS 38-HO-04.
PY - 2012/9
Y1 - 2012/9
N2 - The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.
AB - The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.
KW - Breast cancer
KW - HPV
KW - Invasive ductal Carcinoma
UR - http://www.scopus.com/inward/record.url?scp=84872805637&partnerID=8YFLogxK
U2 - 10.1007/s12032-011-0059-x
DO - 10.1007/s12032-011-0059-x
M3 - Artículo
C2 - 21909942
SN - 1357-0560
VL - 29
SP - 1515
EP - 1517
JO - Medical Oncology
JF - Medical Oncology
IS - 3
ER -