Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population

Lisbeth Herrera-Romano; Nora Fernández-Tamayo; Eduardo Gómez-Conde; Juan M. Reyes-Cardoso; Felipe Ortiz-Gutierrez; Guillermo Ceballos; Alejandra Valdivia; Patricia Piña; Mauricio Salcedo

doi:10.1007/s12032-011-0059-x

Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population

Lisbeth Herrera-Romano, Nora Fernández-Tamayo, Eduardo Gómez-Conde, Juan M. Reyes-Cardoso, Felipe Ortiz-Gutierrez, Guillermo Ceballos, Alejandra Valdivia, Patricia Piña, Mauricio Salcedo

Escuela Superior de Medicina (ESM)

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.

Original language	English
Pages (from-to)	1515-1517
Number of pages	3
Journal	Medical Oncology
Volume	29
Issue number	3
DOIs	https://doi.org/10.1007/s12032-011-0059-x
State	Published - Sep 2012

Keywords

Breast cancer
HPV
Invasive ductal Carcinoma

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title = "Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population",

abstract = "The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.",

keywords = "Breast cancer, HPV, Invasive ductal Carcinoma",

author = "Lisbeth Herrera-Romano and Nora Fern{\'a}ndez-Tamayo and Eduardo G{\'o}mez-Conde and Reyes-Cardoso, {Juan M.} and Felipe Ortiz-Gutierrez and Guillermo Ceballos and Alejandra Valdivia and Patricia Pi{\~n}a and Mauricio Salcedo",

note = "Funding Information: Acknowledgments This work was partially supported by grants 69,719 and 87,244 from Fondos Sectoriales from Consejo Nacional de Ciencia y Tecnolog{\'i}a (CONACyT-M{\'e}xico) and IMSS 38-HO-04.",

year = "2012",

month = sep,

doi = "10.1007/s12032-011-0059-x",

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volume = "29",

pages = "1515--1517",

journal = "Medical Oncology",

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T1 - Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population

AU - Herrera-Romano, Lisbeth

AU - Fernández-Tamayo, Nora

AU - Gómez-Conde, Eduardo

AU - Reyes-Cardoso, Juan M.

AU - Ortiz-Gutierrez, Felipe

AU - Ceballos, Guillermo

AU - Valdivia, Alejandra

AU - Piña, Patricia

AU - Salcedo, Mauricio

N1 - Funding Information: Acknowledgments This work was partially supported by grants 69,719 and 87,244 from Fondos Sectoriales from Consejo Nacional de Ciencia y Tecnología (CONACyT-México) and IMSS 38-HO-04.

PY - 2012/9

Y1 - 2012/9

N2 - The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.

AB - The role of human papillomavirus (HPV) in breast cancer is controversial. We evaluated 118 breast carcinomas and two paraffin-embedded tissues of lesions of the nipple of Mexican patients for HPV sequences. No carcinoma sample exhibited koilocytosis, in contrast to lesions of the nipple. We subjected purified DNAs to PCR employing two HPV16/E6 or GP5/6 primer set oligonucleotides. Results showed that HPV DNA sequences were absent in the breast tissues. Absence of HPV in breast carcinoma failed to support an association between HPV infection and this carcinoma.

KW - Breast cancer

KW - HPV

KW - Invasive ductal Carcinoma

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U2 - 10.1007/s12032-011-0059-x

DO - 10.1007/s12032-011-0059-x

M3 - Artículo

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SN - 1357-0560

VL - 29

SP - 1515

EP - 1517

JO - Medical Oncology

JF - Medical Oncology

IS - 3

ER -

Absence of human papillomavirus sequences in epithelial breast cancer in a Mexican female population

Abstract

Keywords

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