Pharmacology for the fetus and the newborn

Hugo Juarez Olguín, Ismael Lares-Asseff

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

© 2018 by Nova Science Publishers, Inc. All rights reserved. During intrauterine life, the fetus can be exposed to a series of substances ingested by the mother, some of which are necessary for her health but detrimental to the fetus. The noxious effects of such exposure could present in the fetus immediately after exposure or be manifested at the time of delivery and sometimes weeks after birth. The passage of drugs or nutrients across the placenta depends on physicochemical properties of the substances that enable them to cross the placenta barrier, and thus get in contact with the fetus and produce harmful effects. Considering the physicochemical properties of the substances, the possibility of such compounds to cross the placenta barrier and thence to the fetus can be predicted. Equally, it is important to consider the characteristics of the newborn as an immature being, different from adults, when carrying out pharmacokinetic and pharmacodynamic processes. Based on the latter, it is important to know the behavior or characteristics of the fetus and the newborn in the face of drug management and above all, consider the advantages and disadvantages of the use of such drugs for the care of a being yet in development, as described in this work.
Original languageAmerican English
Title of host publicationThe Optimization of Drug Prescribing in Children
Number of pages21
ISBN (Electronic)9781536130263
StatePublished - 1 Jan 2018

Fingerprint

Fetus
Pharmacology
Placenta
Pharmaceutical Preparations
Pharmacokinetics
Parturition
Food
Health

Cite this

Juarez Olguín, H., & Lares-Asseff, I. (2018). Pharmacology for the fetus and the newborn. In The Optimization of Drug Prescribing in Children
Juarez Olguín, Hugo ; Lares-Asseff, Ismael. / Pharmacology for the fetus and the newborn. The Optimization of Drug Prescribing in Children. 2018.
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Juarez Olguín, H & Lares-Asseff, I 2018, Pharmacology for the fetus and the newborn. in The Optimization of Drug Prescribing in Children.

Pharmacology for the fetus and the newborn. / Juarez Olguín, Hugo; Lares-Asseff, Ismael.

The Optimization of Drug Prescribing in Children. 2018.

Research output: Chapter in Book/Report/Conference proceedingChapter

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AB - © 2018 by Nova Science Publishers, Inc. All rights reserved. During intrauterine life, the fetus can be exposed to a series of substances ingested by the mother, some of which are necessary for her health but detrimental to the fetus. The noxious effects of such exposure could present in the fetus immediately after exposure or be manifested at the time of delivery and sometimes weeks after birth. The passage of drugs or nutrients across the placenta depends on physicochemical properties of the substances that enable them to cross the placenta barrier, and thus get in contact with the fetus and produce harmful effects. Considering the physicochemical properties of the substances, the possibility of such compounds to cross the placenta barrier and thence to the fetus can be predicted. Equally, it is important to consider the characteristics of the newborn as an immature being, different from adults, when carrying out pharmacokinetic and pharmacodynamic processes. Based on the latter, it is important to know the behavior or characteristics of the fetus and the newborn in the face of drug management and above all, consider the advantages and disadvantages of the use of such drugs for the care of a being yet in development, as described in this work.

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Juarez Olguín H, Lares-Asseff I. Pharmacology for the fetus and the newborn. In The Optimization of Drug Prescribing in Children. 2018