Pharmacology for the fetus and the newborn

Hugo Juarez Olguín, Ismael Lares-Asseff

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

1 Cita (Scopus)

Resumen

During intrauterine life, the fetus can be exposed to a series of substances ingested by the mother, some of which are necessary for her health but detrimental to the fetus. The noxious effects of such exposure could present in the fetus immediately after exposure or be manifested at the time of delivery and sometimes weeks after birth. The passage of drugs or nutrients across the placenta depends on physicochemical properties of the substances that enable them to cross the placenta barrier, and thus get in contact with the fetus and produce harmful effects. Considering the physicochemical properties of the substances, the possibility of such compounds to cross the placenta barrier and thence to the fetus can be predicted. Equally, it is important to consider the characteristics of the newborn as an immature being, different from adults, when carrying out pharmacokinetic and pharmacodynamic processes. Based on the latter, it is important to know the behavior or characteristics of the fetus and the newborn in the face of drug management and above all, consider the advantages and disadvantages of the use of such drugs for the care of a being yet in development, as described in this work.

Idioma originalInglés
Título de la publicación alojadaThe Optimization of Drug Prescribing in Children
EditorialNova Science Publishers, Inc.
Páginas91-111
Número de páginas21
ISBN (versión digital)9781536130263
ISBN (versión impresa)9781536122633
EstadoPublicada - 1 ene. 2018

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