TY - JOUR
T1 - Diterpenoids from the freshwater green algae Rhizoclonium hieroglyphicum with antibacterial activity
AU - Perez Gutierrez, Rosa Martha
AU - Garcia Baez, Efren
PY - 2011/10
Y1 - 2011/10
N2 - Three new isopimarane diterpenes 7-hydroxy-19-methylmalonyloxy-isopimara- 8(14),15-diene (1), 7β-hydroxy-14-oxo-isopimara-8(9),15-dien-19oic acid (2), and 7β-hydroxy-14-oxo-19α-methylmalonyloxy-isopimara-9(11),15- diene (3) in addition to the known compounds isopimaric acid (4), 7oxo-13-epi-pimara-14,15-dien-18oic acid (5), 7oxo-13-epi-pimara-8,15-dien-18oic acid (6), and 6β-hydroxyisopimaric acid (7) were isolated from the hexane extract of Rhizoclonium hieroglyphicum. The structures of compounds 1-7 were established by 1D and 2D NMR techniques. The isolated diterpenoids were screened for antimicrobial activity against gram-positive and gram-negative bacteria and yeast strains.
AB - Three new isopimarane diterpenes 7-hydroxy-19-methylmalonyloxy-isopimara- 8(14),15-diene (1), 7β-hydroxy-14-oxo-isopimara-8(9),15-dien-19oic acid (2), and 7β-hydroxy-14-oxo-19α-methylmalonyloxy-isopimara-9(11),15- diene (3) in addition to the known compounds isopimaric acid (4), 7oxo-13-epi-pimara-14,15-dien-18oic acid (5), 7oxo-13-epi-pimara-8,15-dien-18oic acid (6), and 6β-hydroxyisopimaric acid (7) were isolated from the hexane extract of Rhizoclonium hieroglyphicum. The structures of compounds 1-7 were established by 1D and 2D NMR techniques. The isolated diterpenoids were screened for antimicrobial activity against gram-positive and gram-negative bacteria and yeast strains.
KW - Rhizoclonium hieroglyphicum
KW - antimicrobial
KW - isopimarane diterpenoids
UR - http://www.scopus.com/inward/record.url?scp=80053648825&partnerID=8YFLogxK
U2 - 10.1080/10286020.2011.601744
DO - 10.1080/10286020.2011.601744
M3 - Artículo
SN - 1028-6020
VL - 13
SP - 934
EP - 941
JO - Journal of Asian Natural Products Research
JF - Journal of Asian Natural Products Research
IS - 10
ER -