Diterpenoids from the freshwater green algae Rhizoclonium hieroglyphicum with antibacterial activity

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Resumen

Three new isopimarane diterpenes 7-hydroxy-19-methylmalonyloxy-isopimara- 8(14),15-diene (1), 7β-hydroxy-14-oxo-isopimara-8(9),15-dien-19oic acid (2), and 7β-hydroxy-14-oxo-19α-methylmalonyloxy-isopimara-9(11),15- diene (3) in addition to the known compounds isopimaric acid (4), 7oxo-13-epi-pimara-14,15-dien-18oic acid (5), 7oxo-13-epi-pimara-8,15-dien-18oic acid (6), and 6β-hydroxyisopimaric acid (7) were isolated from the hexane extract of Rhizoclonium hieroglyphicum. The structures of compounds 1-7 were established by 1D and 2D NMR techniques. The isolated diterpenoids were screened for antimicrobial activity against gram-positive and gram-negative bacteria and yeast strains.

Idioma originalInglés
Páginas (desde-hasta)934-941
Número de páginas8
PublicaciónJournal of Asian Natural Products Research
Volumen13
N.º10
DOI
EstadoPublicada - oct. 2011

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