Design and synthesis of an indole-estrogen derivative

Figueroa Valverde Lauro, Díaz Cedillo Francisco, Rosas Nexticapa Marcela, Hau Heredia Lenin, García Cervera Elodia, Pool Gómez Eduardo, Sarabia Alcocer Betty

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Abstract

There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.

Original languageEnglish
Article number460968
JournalJournal of Chemistry
Volume2014
DOIs
StatePublished - 2014

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