Design and synthesis of an indole-estrogen derivative

Figueroa Valverde Lauro; Díaz Cedillo Francisco; Rosas Nexticapa Marcela; Hau Heredia Lenin; García Cervera Elodia; Pool Gómez Eduardo; Sarabia Alcocer Betty

doi:10.1155/2014/460968

Design and synthesis of an indole-estrogen derivative

Figueroa Valverde Lauro, Díaz Cedillo Francisco, Rosas Nexticapa Marcela, Hau Heredia Lenin, García Cervera Elodia, Pool Gómez Eduardo, Sarabia Alcocer Betty

Escuela Nacional de Ciencias Biológicas (ENCB)

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

2 Citas (Scopus)

Resumen

There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.

Idioma original	Inglés
Número de artículo	460968
Publicación	Journal of Chemistry
Volumen	2014
DOI	https://doi.org/10.1155/2014/460968
Estado	Publicada - 2014

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abstract = "There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.",

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T1 - Design and synthesis of an indole-estrogen derivative

AU - Lauro, Figueroa Valverde

AU - Francisco, Díaz Cedillo

AU - Marcela, Rosas Nexticapa

AU - Lenin, Hau Heredia

AU - Elodia, García Cervera

AU - Eduardo, Pool Gómez

AU - Betty, Sarabia Alcocer

PY - 2014

Y1 - 2014

N2 - There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.

AB - There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2′,3′:17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.

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DO - 10.1155/2014/460968

M3 - Artículo

SN - 2090-9063

VL - 2014

JO - Journal of Chemistry

JF - Journal of Chemistry

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