TY - JOUR
T1 - Colonic Fermentation of Unavailable Carbohydrates from Unripe Banana and its Influence over Glycemic Control
AU - Dan, Milana C.T.
AU - Cardenette, Giselli H.L.
AU - Sardá, Fabiana A.H.
AU - Giuntini, Eliana Bistriche
AU - Bello-Pérez, Luis Arturo
AU - Carpinelli, Ângelo R.
AU - Lajolo, Franco M.
AU - Menezes, Elizabete Wenzel
N1 - Publisher Copyright:
© 2015, Springer Science+Business Media New York.
PY - 2015/9/19
Y1 - 2015/9/19
N2 - The aim of this study was to evaluate the effect of the colonic fermentation of unavailable carbohydrates from unripe banana (mass - UBM - and starch - UBS) over parameters related to glucose and insulin response in rats. Wistar male rats were fed either a control diet, a UBM diet (5 % resistant starch - RS) or a UBS diet (10 % RS) for 28 days. In vivo (oral glucose tolerance test) and in vitro (cecum fecal fermentation, pancreatic islet insulin secretion) analyses were performed. The consumption of UBM and UBS diets by Wistar rats for 28 days improved insulin/glucose ratio. Also, pancreatic islets isolated from the test groups presented significant lower insulin secretion compared to the control group, when the same in vitro glucose stimulation was done. Total short chain fatty acids produced were higher in both experimental groups in relation to the control group. These findings suggest that UBM and UBS diets promote colonic fermentation and can influence glycemic control, improving insulin sensitivity in rats.
AB - The aim of this study was to evaluate the effect of the colonic fermentation of unavailable carbohydrates from unripe banana (mass - UBM - and starch - UBS) over parameters related to glucose and insulin response in rats. Wistar male rats were fed either a control diet, a UBM diet (5 % resistant starch - RS) or a UBS diet (10 % RS) for 28 days. In vivo (oral glucose tolerance test) and in vitro (cecum fecal fermentation, pancreatic islet insulin secretion) analyses were performed. The consumption of UBM and UBS diets by Wistar rats for 28 days improved insulin/glucose ratio. Also, pancreatic islets isolated from the test groups presented significant lower insulin secretion compared to the control group, when the same in vitro glucose stimulation was done. Total short chain fatty acids produced were higher in both experimental groups in relation to the control group. These findings suggest that UBM and UBS diets promote colonic fermentation and can influence glycemic control, improving insulin sensitivity in rats.
KW - Colonic fermentation
KW - Glucose tolerance
KW - Insulin
KW - Unripe banana
UR - http://www.scopus.com/inward/record.url?scp=84939469028&partnerID=8YFLogxK
U2 - 10.1007/s11130-015-0493-6
DO - 10.1007/s11130-015-0493-6
M3 - Artículo
C2 - 26092708
SN - 0921-9668
VL - 70
SP - 297
EP - 303
JO - Plant Foods for Human Nutrition
JF - Plant Foods for Human Nutrition
IS - 3
ER -