Assessment of99mTc-octreotide through a hybrid quantification method

Gerardo Ramírez-Nava; Clara Santos-Cuevas; Isaac Chairez-Oria; Eurídice Rioja-Guerrero; Eleazar Ignacio-Álvarez

doi:10.1063/5.0051123

Assessment of^99mTc-octreotide through a hybrid quantification method

Gerardo Ramírez-Nava, Clara Santos-Cuevas, Isaac Chairez-Oria, Eurídice Rioja-Guerrero, Eleazar Ignacio-Álvarez

Unidad Profesional Interdisciplinaria de Biotecnología (UPIBI)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The conjugate-view counting method used to be the most popular approach to obtain the quantitative information of radiopharmaceuticals. However, the advances in the medical technology and the image processing methods have led to the appearance of new quantification techniques, among which stands out the three-dimensional (3D) quantification of activity in internal tissues of interest. Despite the advantages of this method, its application in nuclear medicine services is usually limited by the workload. In order to exploit the advantages that each quantification method offers, alternative quantitative techniques known as hybrid methods have been developed. This study assessed the quantification of^99mTc-Octreotide through the conjugate-view method (2D) and the hybrid approach (2D/3D) in two patients. The hybrid quantification method improved the dose assessment avoiding the dose overestimation and underestimation in organs and lesions of interest observed in the 2D method.

Original language	English
Title of host publication	Proceedings of the XVI Mexican Symposium on Medical Physics
Editors	Ivan Miguel Rosado-Mendez, Mariana Hernandez-Bojorquez, Jose Hector Morales-Barcenas, Paulina Esther Galavis, Mariela Adelaida Porras-Chaverri
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735440944
DOIs	https://doi.org/10.1063/5.0051123
State	Published - 30 Apr 2021
Event	16th Mexican Symposium on Medical Physics, MSOMP 2020 - Merida, Mexico Duration: 26 Oct 2020 → 30 Oct 2020

Publication series

Name	AIP Conference Proceedings
Volume	2348
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	16th Mexican Symposium on Medical Physics, MSOMP 2020
Country/Territory	Mexico
City	Merida
Period	26/10/20 → 30/10/20

Keywords

Hybrid quantification
Internal Dosimetry
Quantitative SPECT
Radiopharmaceuticals
Tc-Octreotide

Access to Document

10.1063/5.0051123

Cite this

Ramírez-Nava, G., Santos-Cuevas, C., Chairez-Oria, I., Rioja-Guerrero, E., & Ignacio-Álvarez, E. (2021). Assessment of^99mTc-octreotide through a hybrid quantification method. In I. M. Rosado-Mendez, M. Hernandez-Bojorquez, J. H. Morales-Barcenas, P. E. Galavis, & M. A. Porras-Chaverri (Eds.), Proceedings of the XVI Mexican Symposium on Medical Physics Article 0051123 (AIP Conference Proceedings; Vol. 2348). American Institute of Physics Inc.. https://doi.org/10.1063/5.0051123

Ramírez-Nava, Gerardo ; Santos-Cuevas, Clara ; Chairez-Oria, Isaac et al. / Assessment of^99mTc-octreotide through a hybrid quantification method. Proceedings of the XVI Mexican Symposium on Medical Physics. editor / Ivan Miguel Rosado-Mendez ; Mariana Hernandez-Bojorquez ; Jose Hector Morales-Barcenas ; Paulina Esther Galavis ; Mariela Adelaida Porras-Chaverri. American Institute of Physics Inc., 2021. (AIP Conference Proceedings).

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abstract = "The conjugate-view counting method used to be the most popular approach to obtain the quantitative information of radiopharmaceuticals. However, the advances in the medical technology and the image processing methods have led to the appearance of new quantification techniques, among which stands out the three-dimensional (3D) quantification of activity in internal tissues of interest. Despite the advantages of this method, its application in nuclear medicine services is usually limited by the workload. In order to exploit the advantages that each quantification method offers, alternative quantitative techniques known as hybrid methods have been developed. This study assessed the quantification of99mTc-Octreotide through the conjugate-view method (2D) and the hybrid approach (2D/3D) in two patients. The hybrid quantification method improved the dose assessment avoiding the dose overestimation and underestimation in organs and lesions of interest observed in the 2D method.",

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Ramírez-Nava, G, Santos-Cuevas, C, Chairez-Oria, I, Rioja-Guerrero, E & Ignacio-Álvarez, E 2021, Assessment of^99mTc-octreotide through a hybrid quantification method. in IM Rosado-Mendez, M Hernandez-Bojorquez, JH Morales-Barcenas, PE Galavis & MA Porras-Chaverri (eds), Proceedings of the XVI Mexican Symposium on Medical Physics., 0051123, AIP Conference Proceedings, vol. 2348, American Institute of Physics Inc., 16th Mexican Symposium on Medical Physics, MSOMP 2020, Merida, Mexico, 26/10/20. https://doi.org/10.1063/5.0051123

Assessment of^99mTc-octreotide through a hybrid quantification method. / Ramírez-Nava, Gerardo; Santos-Cuevas, Clara; Chairez-Oria, Isaac et al.
Proceedings of the XVI Mexican Symposium on Medical Physics. ed. / Ivan Miguel Rosado-Mendez; Mariana Hernandez-Bojorquez; Jose Hector Morales-Barcenas; Paulina Esther Galavis; Mariela Adelaida Porras-Chaverri. American Institute of Physics Inc., 2021. 0051123 (AIP Conference Proceedings; Vol. 2348).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Ramírez-Nava, Gerardo

AU - Santos-Cuevas, Clara

AU - Chairez-Oria, Isaac

AU - Rioja-Guerrero, Eurídice

AU - Ignacio-Álvarez, Eleazar

PY - 2021/4/30

Y1 - 2021/4/30

N2 - The conjugate-view counting method used to be the most popular approach to obtain the quantitative information of radiopharmaceuticals. However, the advances in the medical technology and the image processing methods have led to the appearance of new quantification techniques, among which stands out the three-dimensional (3D) quantification of activity in internal tissues of interest. Despite the advantages of this method, its application in nuclear medicine services is usually limited by the workload. In order to exploit the advantages that each quantification method offers, alternative quantitative techniques known as hybrid methods have been developed. This study assessed the quantification of99mTc-Octreotide through the conjugate-view method (2D) and the hybrid approach (2D/3D) in two patients. The hybrid quantification method improved the dose assessment avoiding the dose overestimation and underestimation in organs and lesions of interest observed in the 2D method.

AB - The conjugate-view counting method used to be the most popular approach to obtain the quantitative information of radiopharmaceuticals. However, the advances in the medical technology and the image processing methods have led to the appearance of new quantification techniques, among which stands out the three-dimensional (3D) quantification of activity in internal tissues of interest. Despite the advantages of this method, its application in nuclear medicine services is usually limited by the workload. In order to exploit the advantages that each quantification method offers, alternative quantitative techniques known as hybrid methods have been developed. This study assessed the quantification of99mTc-Octreotide through the conjugate-view method (2D) and the hybrid approach (2D/3D) in two patients. The hybrid quantification method improved the dose assessment avoiding the dose overestimation and underestimation in organs and lesions of interest observed in the 2D method.

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KW - Internal Dosimetry

KW - Quantitative SPECT

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M3 - Contribución a la conferencia

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A2 - Rosado-Mendez, Ivan Miguel

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PB - American Institute of Physics Inc.

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Y2 - 26 October 2020 through 30 October 2020

ER -

Ramírez-Nava G, Santos-Cuevas C, Chairez-Oria I, Rioja-Guerrero E, Ignacio-Álvarez E. Assessment of^99mTc-octreotide through a hybrid quantification method. In Rosado-Mendez IM, Hernandez-Bojorquez M, Morales-Barcenas JH, Galavis PE, Porras-Chaverri MA, editors, Proceedings of the XVI Mexican Symposium on Medical Physics. American Institute of Physics Inc. 2021. 0051123. (AIP Conference Proceedings). doi: 10.1063/5.0051123