TY - JOUR
T1 - Toxic effect and bioavailability of malathion spiked in natural sediments from the Ignacio Ramirez dam on the snail Stagnicola sp
AU - Martínez-Tabche, Laura
AU - Galar, M. Marcela
AU - Olvera, H. Elena
AU - Chehue, R. Alejandro
AU - López, Eugenia López
AU - Gómez-Oliván, Leobardo
AU - Sierra, Oscar Terron
PY - 2002
Y1 - 2002
N2 - Malathion (MA) is a widely used insecticide in México. The snail Stagnicola sp is a native species of the Ignacio Ramírez dam (IRD). This work aimed to evaluate the bioavailability and toxicity of MA in sediments of the IRD from the Stagnicola sp snail, taking into account the physicochemical properties of the IRD sediment. The toxic effect of MA on the snail Stagnicola sp was evaluated by biochemical tests of acetylcholinesterase (AchE) activity, protein concentration, lipid peroxidation level (LPL), and lipid content; a toxicokinetic study was also carried out. An increment in all biochemical parameters was observed at the beginning of exposure, while at 48 and 72 h a decrement in AchE activity, LPL, and lipid content was observed. The kinetics study showed gradual uptake and rapid elimination of the insecticide in the test organism. The bioconcentration factor and the absorption and elimination constants led to the conclusion that this compound is not being stored in snails. However, at the end of the experiment, the snails without MA exhibited a lack of recovery in AchE activity, which indicates that there is no correlation between the inhibitory pattern of AchE activity and snail MA concentration.
AB - Malathion (MA) is a widely used insecticide in México. The snail Stagnicola sp is a native species of the Ignacio Ramírez dam (IRD). This work aimed to evaluate the bioavailability and toxicity of MA in sediments of the IRD from the Stagnicola sp snail, taking into account the physicochemical properties of the IRD sediment. The toxic effect of MA on the snail Stagnicola sp was evaluated by biochemical tests of acetylcholinesterase (AchE) activity, protein concentration, lipid peroxidation level (LPL), and lipid content; a toxicokinetic study was also carried out. An increment in all biochemical parameters was observed at the beginning of exposure, while at 48 and 72 h a decrement in AchE activity, LPL, and lipid content was observed. The kinetics study showed gradual uptake and rapid elimination of the insecticide in the test organism. The bioconcentration factor and the absorption and elimination constants led to the conclusion that this compound is not being stored in snails. However, at the end of the experiment, the snails without MA exhibited a lack of recovery in AchE activity, which indicates that there is no correlation between the inhibitory pattern of AchE activity and snail MA concentration.
KW - Acetylcholinesterase
KW - Bioconcentration factor
KW - Elimination
KW - Lipid peroxidation
KW - Lipids
KW - Malathion
KW - Proteins
KW - Snails
KW - Uptake
UR - http://www.scopus.com/inward/record.url?scp=0036020113&partnerID=8YFLogxK
U2 - 10.1006/eesa.2002.2162
DO - 10.1006/eesa.2002.2162
M3 - Artículo
C2 - 12297085
AN - SCOPUS:0036020113
SN - 0147-6513
VL - 52
SP - 232
EP - 237
JO - Ecotoxicology and Environmental Safety
JF - Ecotoxicology and Environmental Safety
IS - 3
ER -