TY - JOUR
T1 - Salmonella - the ultimate insider. Salmonella virulence factors that modulate intracellular survival
AU - Ibarra, J. Antonio
AU - Steele-Mortimer, Olivia
PY - 2009/11
Y1 - 2009/11
N2 - Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen that causes food-borne gastroenteritis in millions of people worldwide. Intracellular survival and replication are important virulence determinants and the bacteria can be found in a variety of phagocytic and non-phagocytic cells in vivo. Invasion of host cells and intracellular survival are dependent on two type III secretion systems, T3SS1 and T3SS2, each of which translocates a distinct set of effector proteins. However, other virulence factors including ion transporters, superoxide dismutase, flagella and fimbriae are also involved in accessing and utilizing the intracellular niche.
AB - Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen that causes food-borne gastroenteritis in millions of people worldwide. Intracellular survival and replication are important virulence determinants and the bacteria can be found in a variety of phagocytic and non-phagocytic cells in vivo. Invasion of host cells and intracellular survival are dependent on two type III secretion systems, T3SS1 and T3SS2, each of which translocates a distinct set of effector proteins. However, other virulence factors including ion transporters, superoxide dismutase, flagella and fimbriae are also involved in accessing and utilizing the intracellular niche.
UR - http://www.scopus.com/inward/record.url?scp=72749111397&partnerID=8YFLogxK
U2 - 10.1111/j.1462-5822.2009.01368.x
DO - 10.1111/j.1462-5822.2009.01368.x
M3 - Artículo de revisión
C2 - 19775254
AN - SCOPUS:72749111397
SN - 1462-5814
VL - 11
SP - 1579
EP - 1586
JO - Cellular Microbiology
JF - Cellular Microbiology
IS - 11
ER -