Recent Advances in the Development of Triose Phosphate Isomerase Inhibitors as Antiprotozoal Agents

Medicina y ciencias biológicas

• Antiprotozoal Agents 95%
• Triose-Phosphate Isomerase 81%
• Parasitic Diseases 11%
• Glycolysis 11%
• Benzoxazoles 9%
• benzothiazole 8%
• Parasites 8%
• Enzymes 8%
• Leishmania mexicana 8%
• benzimidazole 7%
• African Trypanosomiasis 7%
• Trichomonas Infections 7%
• Giardiasis 7%
• Amebiasis 7%
• Trichomonas vaginalis 7%
• Entamoeba histolytica 6%
• Giardia lamblia 6%
• Trypanosoma brucei brucei 6%
• Pharmaceutical Preparations 6%
• Trypanosoma cruzi 6%
• Chagas Disease 6%
• Structure-Activity Relationship 6%
• Leishmaniasis 6%
• Drug Design 6%
• Pyruvic Acid 5%
• Plasmodium falciparum 5%
• Computer Simulation 5%
• Drug Resistance 4%
• Malaria 4%
• Developing Countries 4%
• Catalytic Domain 4%
• Public Health 3%
• Glucose 3%
• In Vitro Techniques 2%
• Therapeutics 1%

Química

• Isomerase Inhibitor 100%
• Antiprotozoal Agent 86%
• Triose 78%
• Phosphate 34%
• Parasitic 13%
• Benzoxazole 6%
• Enzyme Inhibition 6%
• Quaternary Structure 6%
• Benzothiazole 6%
• Drug 5%
• Tertiary Structure 5%
• Benzimidazole 5%
• Pyruvate 5%
• Energy 4%
• Structure-Activity Relationship 4%
• Glucose 3%
• Pharmaceutical 3%