TY - JOUR
T1 - Potential use of wood metabolites for cancer treatment
AU - Ibarra-Berumen, Jorge
AU - Rosales-Castro, Martha
AU - Ordaz-Pichardo, Cynthia
N1 - Publisher Copyright:
© 2021 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - The study of medicinal plants for cancer treatment has gained attention due to an increasing incidence of cancer worldwide and antineoplastics-related undesirable secondary effects. Most of the natural products of medicinal plants that have been evaluated for cytotoxic activity, are derived from leaves, bark, roots and flowers. However, natural products derived from wood have demonstrated a cytotoxic effect with promising results. Moreover, some fractions and compounds have been isolated of wood in order to increase the effect. This review presents in vitro experimental evidence of cytotoxic effect of natural products from wood against cancer cell lines. It also provides considerations and recommendations to obtain herbal medicines over time.
AB - The study of medicinal plants for cancer treatment has gained attention due to an increasing incidence of cancer worldwide and antineoplastics-related undesirable secondary effects. Most of the natural products of medicinal plants that have been evaluated for cytotoxic activity, are derived from leaves, bark, roots and flowers. However, natural products derived from wood have demonstrated a cytotoxic effect with promising results. Moreover, some fractions and compounds have been isolated of wood in order to increase the effect. This review presents in vitro experimental evidence of cytotoxic effect of natural products from wood against cancer cell lines. It also provides considerations and recommendations to obtain herbal medicines over time.
KW - Wood extract
KW - apoptosis
KW - cancer cell lines
KW - cytotoxicity
KW - phenolic compounds
UR - http://www.scopus.com/inward/record.url?scp=85113858489&partnerID=8YFLogxK
U2 - 10.1080/14786419.2021.1972420
DO - 10.1080/14786419.2021.1972420
M3 - Artículo de revisión
C2 - 34459687
AN - SCOPUS:85113858489
SN - 1478-6419
VL - 36
SP - 4293
EP - 4309
JO - Natural Product Research
JF - Natural Product Research
IS - 16
ER -