Participación de las especies reactivas del oxígeno en las enfermedades pulmonares

Martha Patricia Sierra Vargas; Alberto Martín Guzmán-Grenfell; Ivonne María Olivares-Corichi; Yessica Dorin Torres Ramos; Juan José Hicks Gómez

Participación de las especies reactivas del oxígeno en las enfermedades pulmonares

Martha Patricia Sierra Vargas, Alberto Martín Guzmán-Grenfell, Ivonne María Olivares-Corichi, Yessica Dorin Torres Ramos, Juan José Hicks Gómez

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

6 Citas (Scopus)

Resumen

Reactive Oxygen Species (ROS) are very reactive molecules (O ₂ ^•-, HO ^•, NO ^•) since they have a single and unpaired electron in the last orbital (free radical) which confers them physical instability. Free radical precursors such as H ₂O ₂, HONO ₂ ^- are considered ROS. These species are important in the physiological processes. When ROS production exceeds the inactivation mechanisms, oxidative stress takes place. This stress is characterized by molecular and cellular damage which predisposes to or modifies chronic-degenerative diseases. Among pulmonary diseases in which ROS participation has been proved are ARDS, COPD and asthma. The aim of this paper was to analyze the mechanisms of oxidative stress that lead to those illnesses.

Título traducido de la contribución	Reactive Oxygen Species (ROS) participation in pulmonary diseases
Idioma original	Español
Páginas (desde-hasta)	135-148
Número de páginas	14
Publicación	Revista del Instituto Nacional de Enfermedades Respiratorias
Volumen	17
N.º	2
Estado	Publicada - abr. 2004
Publicado de forma externa	Sí

Palabras clave

Diseases
Free radicals
Lung
Oxidative injuries
Oxidative stress
Reactive oxygen species

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title = "Participaci{\'o}n de las especies reactivas del ox{\'i}geno en las enfermedades pulmonares",

abstract = "Reactive Oxygen Species (ROS) are very reactive molecules (O 2 •-, HO •, NO •) since they have a single and unpaired electron in the last orbital (free radical) which confers them physical instability. Free radical precursors such as H 2O 2, HONO 2 - are considered ROS. These species are important in the physiological processes. When ROS production exceeds the inactivation mechanisms, oxidative stress takes place. This stress is characterized by molecular and cellular damage which predisposes to or modifies chronic-degenerative diseases. Among pulmonary diseases in which ROS participation has been proved are ARDS, COPD and asthma. The aim of this paper was to analyze the mechanisms of oxidative stress that lead to those illnesses.",

keywords = "Diseases, Free radicals, Lung, Oxidative injuries, Oxidative stress, Reactive oxygen species",

author = "Vargas, {Martha Patricia Sierra} and Guzm{\'a}n-Grenfell, {Alberto Mart{\'i}n} and Olivares-Corichi, {Ivonne Mar{\'i}a} and Ramos, {Yessica Dorin Torres} and G{\'o}mez, {Juan Jos{\'e} Hicks}",

year = "2004",

month = apr,

language = "Espa{\~n}ol",

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pages = "135--148",

journal = "Revista del Instituto Nacional de Enfermedades Respiratorias",

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Participación de las especies reactivas del oxígeno en las enfermedades pulmonares. / Vargas, Martha Patricia Sierra; Guzmán-Grenfell, Alberto Martín; Olivares-Corichi, Ivonne María et al.
En: Revista del Instituto Nacional de Enfermedades Respiratorias, Vol. 17, N.º 2, 04.2004, p. 135-148.

Producción científica: Contribución a una revista › Artículo de revisión › revisión exhaustiva

TY - JOUR

T1 - Participación de las especies reactivas del oxígeno en las enfermedades pulmonares

AU - Vargas, Martha Patricia Sierra

AU - Guzmán-Grenfell, Alberto Martín

AU - Olivares-Corichi, Ivonne María

AU - Ramos, Yessica Dorin Torres

AU - Gómez, Juan José Hicks

PY - 2004/4

Y1 - 2004/4

N2 - Reactive Oxygen Species (ROS) are very reactive molecules (O 2 •-, HO •, NO •) since they have a single and unpaired electron in the last orbital (free radical) which confers them physical instability. Free radical precursors such as H 2O 2, HONO 2 - are considered ROS. These species are important in the physiological processes. When ROS production exceeds the inactivation mechanisms, oxidative stress takes place. This stress is characterized by molecular and cellular damage which predisposes to or modifies chronic-degenerative diseases. Among pulmonary diseases in which ROS participation has been proved are ARDS, COPD and asthma. The aim of this paper was to analyze the mechanisms of oxidative stress that lead to those illnesses.

AB - Reactive Oxygen Species (ROS) are very reactive molecules (O 2 •-, HO •, NO •) since they have a single and unpaired electron in the last orbital (free radical) which confers them physical instability. Free radical precursors such as H 2O 2, HONO 2 - are considered ROS. These species are important in the physiological processes. When ROS production exceeds the inactivation mechanisms, oxidative stress takes place. This stress is characterized by molecular and cellular damage which predisposes to or modifies chronic-degenerative diseases. Among pulmonary diseases in which ROS participation has been proved are ARDS, COPD and asthma. The aim of this paper was to analyze the mechanisms of oxidative stress that lead to those illnesses.

KW - Diseases

KW - Free radicals

KW - Lung

KW - Oxidative injuries

KW - Oxidative stress

KW - Reactive oxygen species

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M3 - Artículo de revisión

SN - 0187-7585

VL - 17

SP - 135

EP - 148

JO - Revista del Instituto Nacional de Enfermedades Respiratorias

JF - Revista del Instituto Nacional de Enfermedades Respiratorias

IS - 2

ER -

Participación de las especies reactivas del oxígeno en las enfermedades pulmonares

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Palabras clave

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