TY - JOUR
T1 - Origin and genetic differentiation of three Native Mexican groups (Purépechas, Triquis and Mayas)
T2 - Contribution of CODIS-STRs to the history of human populations of Mesoamerica
AU - Martínez-Cortés, G.
AU - Nuño-Arana, I.
AU - Rubi-Castellanos, R.
AU - Vilchis-Dorantes, G.
AU - Luna-Vázquez, A.
AU - Coral-Vázquez, R. M.
AU - Canto-Cetina, T.
AU - Salazar-Flores, J.
AU - Muñoz-Valle, J. F.
AU - Sandoval-Mendoza, K.
AU - López, Z.
AU - Gamero-Lucas, J. J.
AU - Rangel-Villalobos, H.
PY - 2010/11
Y1 - 2010/11
N2 - Background: CODIS-STRs in Native Mexican groups have rarely been analysed for human identification and anthropological purposes. Aim: To analyse the genetic relationships and population structure among three Native Mexican groups from Mesoamerica. Subjects and methods: 531 unrelated Native individuals from Mexico were PCR-typed for 15 and 9 autosomal STRs (Identifiler™ and Profiler™ kits, respectively), including five population samples: Purépechas (Mountain, Valley and Lake), Triquis and Yucatec Mayas. Previously published STR data were included in the analyses. Results: Allele frequencies and statistical parameters of forensic importance were estimated by population. The majority of Native groups were not differentiated pairwise, excepting Triquis and Purépechas, which was attributable to their relative geographic and cultural isolation. Although Mayas, Triquis and Purépechas-Mountain presented the highest number of private alleles, suggesting recurrent gene flow, the elevated differentiation of Triquis indicates a different origin of this gene flow. Interestingly, Huastecos and Mayas were not differentiated, which is in agreement with the archaeological hypothesis that Huastecos represent an ancestral Maya group. Interpopulation variability was greater in Natives than in Mestizos, both significant. Conclusion: Although results suggest that European admixture has increased the similarity between Native Mexican groups, the differentiation and inconsistent clustering by language or geography stresses the importance of serial founder effect and/or genetic drift in showing their present genetic relationships.
AB - Background: CODIS-STRs in Native Mexican groups have rarely been analysed for human identification and anthropological purposes. Aim: To analyse the genetic relationships and population structure among three Native Mexican groups from Mesoamerica. Subjects and methods: 531 unrelated Native individuals from Mexico were PCR-typed for 15 and 9 autosomal STRs (Identifiler™ and Profiler™ kits, respectively), including five population samples: Purépechas (Mountain, Valley and Lake), Triquis and Yucatec Mayas. Previously published STR data were included in the analyses. Results: Allele frequencies and statistical parameters of forensic importance were estimated by population. The majority of Native groups were not differentiated pairwise, excepting Triquis and Purépechas, which was attributable to their relative geographic and cultural isolation. Although Mayas, Triquis and Purépechas-Mountain presented the highest number of private alleles, suggesting recurrent gene flow, the elevated differentiation of Triquis indicates a different origin of this gene flow. Interestingly, Huastecos and Mayas were not differentiated, which is in agreement with the archaeological hypothesis that Huastecos represent an ancestral Maya group. Interpopulation variability was greater in Natives than in Mestizos, both significant. Conclusion: Although results suggest that European admixture has increased the similarity between Native Mexican groups, the differentiation and inconsistent clustering by language or geography stresses the importance of serial founder effect and/or genetic drift in showing their present genetic relationships.
KW - CODIS
KW - Mexico
KW - Native groups, Mesoamerica
KW - STRs
UR - http://www.scopus.com/inward/record.url?scp=77958527932&partnerID=8YFLogxK
U2 - 10.3109/03014461003743801
DO - 10.3109/03014461003743801
M3 - Artículo
C2 - 20515366
SN - 0301-4460
VL - 37
SP - 801
EP - 819
JO - Annals of Human Biology
JF - Annals of Human Biology
IS - 6
ER -