TY - JOUR
T1 - Nanosilver gel as an endodontic alternative against Enterococcus faecalis in an in vitro root canal system in Mexican dental specimens
AU - Marín-Correa, Balvir M.
AU - Guzmán-Martínez, Nayelli
AU - Gómez-Ramírez, Marlenne
AU - Pless, Reynaldo C.
AU - Mundo, José R.
AU - García-Ramos, Juan C.
AU - Rojas-Avelizapa, Norma G.
AU - Pestryakov, Alexey
AU - Bogdanchikova, Nina
AU - Fierros-Romero, Grisel
N1 - Publisher Copyright:
© 2020 by EDIMES - Edizioni Internazionali Srl. All rights reserved.
PY - 2020/10
Y1 - 2020/10
N2 - Nanotechnology has become a research area with promising results for technological innovation. Endodontics can benefit from this field of research by increasing the success rate of the treatment, which currently ranges between 86% and 98% and has varied very little over the years. One of the causes of endodontic treatment failure is based on the presence of Enterococcus faecalis. The objective of this investigation is to evaluate the antibacterial effect of a gel preparation containing silver nanoparticles (Ag-NP) against E. faecalis present in the walls of the root canal. 60 extracted human uniradicular teeth that were instrumented with Wave One Gold (Denstplay/USA) and subsequently contaminated with Enterococcus faecalis. For antibacterial evaluation, intra-canal conducting was placed, and several groups were formed: a) Ag-NP 300 ug/MI gel; b) Ag-NP 500 ug/MI gel; c) Ca (OH) 2 (Ultracal from Ultradent/USA) and the control group. They were incubated at 37°C and a sample was taken every 24 h for 7 days. The Ag-NP gel showed antimicrobial activity against E. faecalis with a value of minimum inhibitory concentration and minimum bactericidal concentration of 300 g/ml and 900 g/ml, respectively. When the Ag-NP gel was used as an intra-canal conducting drug in an in-vitro model, its antimicrobial effect at 300 g/ml and 500 g/ml was equivalent to the action of Ca(OH)2,.
AB - Nanotechnology has become a research area with promising results for technological innovation. Endodontics can benefit from this field of research by increasing the success rate of the treatment, which currently ranges between 86% and 98% and has varied very little over the years. One of the causes of endodontic treatment failure is based on the presence of Enterococcus faecalis. The objective of this investigation is to evaluate the antibacterial effect of a gel preparation containing silver nanoparticles (Ag-NP) against E. faecalis present in the walls of the root canal. 60 extracted human uniradicular teeth that were instrumented with Wave One Gold (Denstplay/USA) and subsequently contaminated with Enterococcus faecalis. For antibacterial evaluation, intra-canal conducting was placed, and several groups were formed: a) Ag-NP 300 ug/MI gel; b) Ag-NP 500 ug/MI gel; c) Ca (OH) 2 (Ultracal from Ultradent/USA) and the control group. They were incubated at 37°C and a sample was taken every 24 h for 7 days. The Ag-NP gel showed antimicrobial activity against E. faecalis with a value of minimum inhibitory concentration and minimum bactericidal concentration of 300 g/ml and 900 g/ml, respectively. When the Ag-NP gel was used as an intra-canal conducting drug in an in-vitro model, its antimicrobial effect at 300 g/ml and 500 g/ml was equivalent to the action of Ca(OH)2,.
KW - Ag-NP
KW - Enterococcus faecalis
KW - Nanosilver gel
KW - Root-canal system
UR - http://www.scopus.com/inward/record.url?scp=85097570383&partnerID=8YFLogxK
M3 - Artículo
C2 - 33135081
AN - SCOPUS:85097570383
SN - 1121-7138
VL - 43
SP - 166
EP - 170
JO - New Microbiologica
JF - New Microbiologica
IS - 4
ER -