Resumen
The key step in the synthesis of the anthracyclin precursor 2, the simultaneous formation of the ring A and the 18‐membered lactone ring, proceeds astonishingly in 58% yield by intramolecular Diels‐Alder reaction of 1, R(CH2)6OCOCHCH2.The analogue of 1 with three instead of six methylene groups does not cyclize. (Figure Presented.)
Idioma original | Inglés |
---|---|
Páginas (desde-hasta) | 74-75 |
Número de páginas | 2 |
Publicación | Angewandte Chemie - International Edition |
Volumen | 23 |
N.º | 1 |
DOI | |
Estado | Publicada - ene. 1984 |
Publicado de forma externa | Sí |