LEPRA MURINA EXPERIMENTAL. EFFECTO SOBRE ALGUNAS ENZIMAS PRESENTES EN EL SUERO

This paper presents the results of a study in mice infected with Mycobacterium lepraemurium on the levels of serum alkaline phosphatase, lactatedehydrogenase, glutamate-oxalacetate and glutamate-pyruvate transaminases. The murine mycobacteriosis provokes an increase in the levels of LDH and in the levels of both transaminases but does not modify the level of alkaline phosphatase. Although the increase in the LDH level is the most remarkable, the increase in the levels of GOT and GPT starts earlier and seems to correlate better with the leprosy infection. Measurement of these enzyme activities is proposed as a means to establish and to follow from the beginning the progress of the infection under stuy.