TY - JOUR
T1 - Bloodstream infection by Rhodococcus corynebacterioides in a pediatric patient diagnosed with high-risk retinoblastoma
AU - Méndez-Cruz, Ana Rosa
AU - Félix-Bermúdez, Georgina Elizabeth
AU - Aguilar-Escobar, Dinora Virginia
AU - Vega-Vega, Lourdes
AU - Morales-Estrada, Aurea Itzel
AU - Contreras-Rodríguez, Araceli
N1 - Publisher Copyright:
© 2022 Asociación Argentina de Microbiología
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.
AB - Rhodococcus is a pathogen that is known to cause infections in animals and humans, mainly in cases of immunocompromised patients. A case of a pediatric cancer patient suffering from a bloodstream infection caused by Rhodococcus corynebacterioides was described in this work. Gram positive rods were isolated from blood cultures. The target bacterium was identified using a combination of biochemical tests, the MALDI-TOF mass spectrometry technique, and the analysis of the 16S rRNA sequence. Moreover, an antimicrobial susceptibility test was performed using the E-test. The isolated bacterium was identified as R. corynebacterioides. The 3-year-old patient was successfully treated with vancomycin and meropenem. This is the first published report of R. corynebacterioides in a pediatric patient diagnosed with retinoblastoma that developed a bloodstream infection. R. corynebacterioides should be considered among the opportunistic infectious agents affecting pediatric cancer patients.
KW - Actinomycete
KW - Bacteremia
KW - Bloodstream infection
KW - Cancer
KW - Identification methods
KW - Retinoblastoma
KW - Rhodococcus corynebacterioides
UR - http://www.scopus.com/inward/record.url?scp=85136220325&partnerID=8YFLogxK
U2 - 10.1016/j.ram.2022.06.001
DO - 10.1016/j.ram.2022.06.001
M3 - Artículo
C2 - 35988003
AN - SCOPUS:85136220325
SN - 0325-7541
VL - 55
SP - 68
EP - 72
JO - Revista Argentina de Microbiologia
JF - Revista Argentina de Microbiologia
IS - 1
ER -