Green synthesis of copper (0) nanoparticles with cyanidine-O-3-glucoside and its strong antimicrobial activity

Cu nanoparticles (CuNPs) were biosynthesized by green nanotechnology and they showed a inhibitory power on the growth of Gram (+) and Gram (−). CuNPs synthesis (0) was performed at 65 °C from a solution of copper chloride and using as reducing cyanidine-O-3-glucoside, selectively obtained from the skin of red plum (Pronus domestic). Their characterization has shown typical UV–Vis bands, Cu nanoparticles refers to surface plasmon resonance (SPR) at 550 nm. Structural analysis by HRTEM evidence growth is in the (1 1 1) plane of the fcc phase of metallic Cu, with a size close to 10 nm, with a quasi-spherical morphology, due to the role as surfactant of the cyanidine-O-3-glucoside for the preparation of metal nanoparticles.