TY - JOUR
T1 - Genomics approaches in the understanding of Entamoeba histolytica virulence and gene expression regulation
AU - López-Camarillo, César
AU - Guillen, Nancy
AU - Weber, Christian
AU - Orozco, Esther
AU - Marchat, Laurence A.
PY - 2009/4/20
Y1 - 2009/4/20
N2 - Entamoeba histolytica is the intestinal protozoan parasite responsible for amebic colitis and liver abscesses, which cause mortality in many developing countries. The sequencing of the parasite genome provides new insights into the cellular workings and genome evolution of this major human pathogen. Here, we reviewed recent advances in the efforts to understand virulence and gene expression regulation in E. histolytica by using genomic approaches based on microarray technology and bioinformatic analysis of genome sequence.
AB - Entamoeba histolytica is the intestinal protozoan parasite responsible for amebic colitis and liver abscesses, which cause mortality in many developing countries. The sequencing of the parasite genome provides new insights into the cellular workings and genome evolution of this major human pathogen. Here, we reviewed recent advances in the efforts to understand virulence and gene expression regulation in E. histolytica by using genomic approaches based on microarray technology and bioinformatic analysis of genome sequence.
KW - Amoebiasis
KW - Cdna microarrays
KW - Entamoeba histolytica
KW - Gene families
KW - Genome sequence
KW - Genomic expression profiling
KW - Virulence
UR - http://www.scopus.com/inward/record.url?scp=66749117385&partnerID=8YFLogxK
M3 - Artículo de revisión
SN - 1684-5315
VL - 8
SP - 1363
EP - 1369
JO - African Journal of Biotechnology
JF - African Journal of Biotechnology
IS - 8
ER -