TY - JOUR
T1 - Factores asociados a muerte en niños con covid-19 en méxico
AU - Rivas-Ruiz, Rodolfo
AU - Roy-García, Ivonne A.
AU - Ureña-Wong, Kingston R.
AU - Aguilar-Ituarte, Felipe
AU - Vázquez-De Anda, Gilberto F.
AU - Gutiérrez-Castrellón, Pedro
AU - Mancilla-Ramírez, Javier
AU - Moreno-Espinosa, Sarbelio
N1 - Publisher Copyright:
© 2020 Academia Nacional de Medicina de México, A.C. Publicado por Permanyer.
PY - 2020
Y1 - 2020
N2 - Introduction: Most children affected by SARS-CoV-2 are reported to be asymptomatic, and COVID-19-related mortality in them is low; in Mexico, there is a lack of information on the subject in this population group. Objective: To assess the risk factors associated with mortality in Mexican children with COVID-19. Method: Secondary analysis of the General Directorate of Epidemiology database. Children younger than 19 years, in whom SARS-CoV-2 infection was confirmed by RT-PCR, were included. Results: 1443 children were included. Median age was eight years; 3.3 % were admitted to the intensive care unit, 1.8 % required assisted mechanical ventilation, and mortality was 1.9 %. In multivariate models, the development of pneumonia was the main risk factor for mortality, with an odds ratio (OR) of 6.45 (95 % CI 1.99, 20.89); patients who required intubation had an OR of 8.75 (95 % CI 3.23, 23.7). Conclusions: Children with COVID-19 exhibit high mortality in Mexico, and avoiding pneumonia should therefore be tried in them, especially in children younger than four years with cardiovascular risk or immu-nosuppression.
AB - Introduction: Most children affected by SARS-CoV-2 are reported to be asymptomatic, and COVID-19-related mortality in them is low; in Mexico, there is a lack of information on the subject in this population group. Objective: To assess the risk factors associated with mortality in Mexican children with COVID-19. Method: Secondary analysis of the General Directorate of Epidemiology database. Children younger than 19 years, in whom SARS-CoV-2 infection was confirmed by RT-PCR, were included. Results: 1443 children were included. Median age was eight years; 3.3 % were admitted to the intensive care unit, 1.8 % required assisted mechanical ventilation, and mortality was 1.9 %. In multivariate models, the development of pneumonia was the main risk factor for mortality, with an odds ratio (OR) of 6.45 (95 % CI 1.99, 20.89); patients who required intubation had an OR of 8.75 (95 % CI 3.23, 23.7). Conclusions: Children with COVID-19 exhibit high mortality in Mexico, and avoiding pneumonia should therefore be tried in them, especially in children younger than four years with cardiovascular risk or immu-nosuppression.
KW - Children
KW - Coronavirus disease 2019
KW - Mortality
KW - Pneumonia
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=85102851733&partnerID=8YFLogxK
U2 - 10.24875/GMM.20000478
DO - 10.24875/GMM.20000478
M3 - Artículo
C2 - 33877105
AN - SCOPUS:85102851733
SN - 0016-3813
VL - 156
SP - 526
EP - 532
JO - Gaceta Medica de Mexico
JF - Gaceta Medica de Mexico
IS - 6
ER -