Esters of Quinoxaline-7-carboxylate 1,4-di-N-oxide as Potential Inhibitors of Glycolytic Enzymes of Entamoeba histolytica: In silico Approach

Medicina y ciencias biológicas

• Quinoxalines 100%
• Entamoeba histolytica 90%
• Oxides 81%
• Enzyme Inhibitors 78%
• Molecular Dynamics Simulation 76%
• Esters 69%
• Orthophosphate Dikinase Pyruvate 65%
• Computer Simulation 64%
• Parasites 56%
• Triose-Phosphate Isomerase 52%
• Phosphofructokinases 47%
• Amebiasis 46%
• Enzymes 37%
• Glycogen 35%
• Energy Metabolism 30%
• Software 25%
• Proteins 25%
• Growth 17%

Química

• Amebicide Agent 59%
• Kd 51%
• Molecular Dynamics 50%
• Ester 41%
• Glycogen 41%
• Pyruvate 35%
• Non Toxic 34%
• Protein 28%
• Pharmacological Metabolism 26%
• Phosphate 22%
• Simulation 21%
• Energy 16%