TY - JOUR
T1 - Efficient synthesis of sulfonamide derivatives on solid supports catalyzed using solvent-free and microwave-assisted methods
AU - Camargo-Ordoñez, Argelia
AU - Moreno-Reyes, Christian
AU - Olazarán-Santibáñez, Fabián
AU - Martínez-Hernández, Sheila
AU - Bocanegra-García, Virgilio
AU - Rivera, Gildardo
PY - 2011
Y1 - 2011
N2 - In this work we report the synthesis of sulfonamide derivatives using a conventional procedure and with solid supports, such as silica gel, florisil, alumina, 4Å molecular sieves, montmorillonite KSF, and montmorillonite K10 using solvent-free and microwave-assisted methods. Our results show that solid supports have a catalytic activity in the formation of sulfonamide derivatives. We found that florisil, montmorillonite KSF, and K10 could be used as inexpensive alternative catalysts that are easily separated from the reaction media. Additionally, solvent-free and microwave-assisted methods were more efficient in reducing reaction time and in increasing yield.
AB - In this work we report the synthesis of sulfonamide derivatives using a conventional procedure and with solid supports, such as silica gel, florisil, alumina, 4Å molecular sieves, montmorillonite KSF, and montmorillonite K10 using solvent-free and microwave-assisted methods. Our results show that solid supports have a catalytic activity in the formation of sulfonamide derivatives. We found that florisil, montmorillonite KSF, and K10 could be used as inexpensive alternative catalysts that are easily separated from the reaction media. Additionally, solvent-free and microwave-assisted methods were more efficient in reducing reaction time and in increasing yield.
KW - Solid supports
KW - Sulfonamide
KW - Synthesis
UR - http://www.scopus.com/inward/record.url?scp=79960982559&partnerID=8YFLogxK
M3 - Artículo
SN - 0100-4042
VL - 34
SP - 787
EP - 791
JO - Quimica Nova
JF - Quimica Nova
IS - 5
ER -