Cytotoxic effect of Kalanchoe flammea and induction of intrinsic mitochondrial apoptotic signaling in prostate cancer cells

Medicina y ciencias biológicas

• Kalanchoe 100%
• Micronucleus Tests 47%
• Prostatic Neoplasms 44%
• Phosphatidylserines 43%
• Cytochromes 43%
• Crassulaceae 35%
• Inhibitory Concentration 50 34%
• Caspase 3 33%
• Coumaric Acids 31%
• Reactive Oxygen Species 30%
• X-Linked Inhibitor of Apoptosis Protein 28%
• diacetyldichlorofluorescein 26%
• Palmitic Acid 23%
• PC-3 Cells 23%
• Apoptosis 22%
• ethyl acetate 22%
• Cell Line 22%
• Safety 21%
• Annexin A5 21%
• Medicinal Plants 20%
• DNA Fragmentation 20%
• Mexico 19%
• Traditional Medicine 19%
• Biological Assay 19%
• Cell Cycle Checkpoints 18%
• Toxicology 18%
• Drug Development 17%
• Prostate 15%
• Cell Death 14%
• Pharmacokinetics 14%
• Fever 14%
• Down-Regulation 13%
• Western Blotting 12%
• Clinical Trials 12%
• Inflammation 11%
• Wounds and Injuries 9%
• In Vitro Techniques 8%
• Pharmaceutical Preparations 7%
• Proteins 6%
• Therapeutics 6%
• Neoplasms 6%

Química

• Cytochrome C 78%
• Apoptotic 64%
• Reactive Oxygen Metabolite 53%
• Safety 48%
• Coumaric Acid 43%
• Acute Toxicity 33%
• Cell Death 30%
• Ethyl Acetate 25%
• Fractionation 24%
• Protein 23%
• Fragmentation 23%
• Pharmacokinetics 21%
• Pharmaceutical 20%
• Drug 14%
• Acid 9%