TY - JOUR
T1 - Blue Maize Extract Improves Blood Pressure, Lipid Profiles, and Adipose Tissue in High-Sucrose Diet-Induced Metabolic Syndrome in Rats
AU - Guzmán-Gerónimo, Rosa Isela
AU - Alarcón-Zavaleta, Tania Margarita
AU - Oliart-Ros, Rosa María
AU - Meza-Alvarado, José Enrique
AU - Herrera-Meza, Socorro
AU - Chávez-Servia, José Luis
N1 - Publisher Copyright:
© Copyright 2017, Mary Ann Liebert, Inc., and Korean Society of Food Science and Nutrition.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - The effect of blue maize extract in factors related to metabolic syndrome (MS) in Wistar rats was investigated. Total polyphenols, monomeric anthocyanins, and antioxidant activity were analyzed in blue maize. MS was induced in Wistar rats fed with high-sucrose (HS) diet for 12 weeks. During a period of 4 weeks, blue maize extract was administrated to HS groups fed with high-sucrose and high-cholesterol-high-sucrose (HS+C) diets. In the blue maize extract administered by orogastric cannulation, the levels of total polyphenols and anthocyanins were 9.97 and 2.92 mg/kg of weight, respectively. HS diet administered during a period of 12 weeks increased significantly systolic blood pressure, serum triglycerides, and decreased high-density lipoprotein cholesterol (HDL-C), alterations related to the MS. Abdominal adipose tissue was only increased in the HS + C group. Blue maize extract administration enhanced HDL-C and decreased systolic blood pressure, serum triglycerides, total cholesterol, and epididymal adipose tissue weight. The blue maize may represent a promising nutraceutical option for the treatment of MS.
AB - The effect of blue maize extract in factors related to metabolic syndrome (MS) in Wistar rats was investigated. Total polyphenols, monomeric anthocyanins, and antioxidant activity were analyzed in blue maize. MS was induced in Wistar rats fed with high-sucrose (HS) diet for 12 weeks. During a period of 4 weeks, blue maize extract was administrated to HS groups fed with high-sucrose and high-cholesterol-high-sucrose (HS+C) diets. In the blue maize extract administered by orogastric cannulation, the levels of total polyphenols and anthocyanins were 9.97 and 2.92 mg/kg of weight, respectively. HS diet administered during a period of 12 weeks increased significantly systolic blood pressure, serum triglycerides, and decreased high-density lipoprotein cholesterol (HDL-C), alterations related to the MS. Abdominal adipose tissue was only increased in the HS + C group. Blue maize extract administration enhanced HDL-C and decreased systolic blood pressure, serum triglycerides, total cholesterol, and epididymal adipose tissue weight. The blue maize may represent a promising nutraceutical option for the treatment of MS.
KW - adiposity
KW - dietary-induced hyperlipidemia
KW - hypertension
KW - phenolic compounds
UR - http://www.scopus.com/inward/record.url?scp=85011344940&partnerID=8YFLogxK
U2 - 10.1089/jmf.2016.0087
DO - 10.1089/jmf.2016.0087
M3 - Artículo
C2 - 27977322
SN - 1096-620X
VL - 20
SP - 110
EP - 115
JO - Journal of Medicinal Food
JF - Journal of Medicinal Food
IS - 2
ER -