TY - JOUR
T1 - Bench-scale reactor for Cefadroxil oxidation and elimination of its antibiotic activity using electro-generated active chlorine
AU - Moreno-Palacios, Angie V.
AU - Palma-Goyes, Ricardo E.
AU - Vazquez-Arenas, Jorge
AU - Torres-Palma, Ricardo A.
N1 - Publisher Copyright:
© 2019 Elsevier Ltd
PY - 2019/6
Y1 - 2019/6
N2 - The Cefadroxil (CFDX) degradation and its associated antibiotic activity (AA) are analyzed on Sb2O3 doped Ti/RuO2-ZrO2 anodes electro-generating active chlorine (Cl2-active). The influence of the following parameters: (i) current density (ii) CFDX concentration (iii) volumetric flow and (iv) initial pH is evaluated in a filter-press FM01-LC reactor to account for controlling factors of the system. The CFDX removal is improved when HClO predominate in solution due to its higher oxidation potential, co-assisted with the presence of Cl2 (pH = 2), while the CFDX molecule undergoes a slight acid hydrolysis. The contaminant destruction is controlled by the kinetics arising between the active chlorine species adsorbed on the electrode surface (HClOads) and the pollutant, since the increase of flow rate in the reactor does not improve the abatement whatsoever. The total CFDX concentration and its antibiotic activity can be eliminated after 15 min using electro-generated active chlorine at the following operating conditions: 0.05 mol L−1 NaCl, natural pH (5.5), 3 mA cm−2 and 4 L min−1. The energy consumption is considerably influenced by the cell voltage and the presence of active chlorine and H+ concentrations. An important biodegradability degree of the final byproducts is produced by active chlorine species, while only two intermediates of cefadroxil oxidation (CFDX-I-1 and CFDX-I-2) are detected after 2 h of treatment using high-performance liquid chromatography (HPLC).
AB - The Cefadroxil (CFDX) degradation and its associated antibiotic activity (AA) are analyzed on Sb2O3 doped Ti/RuO2-ZrO2 anodes electro-generating active chlorine (Cl2-active). The influence of the following parameters: (i) current density (ii) CFDX concentration (iii) volumetric flow and (iv) initial pH is evaluated in a filter-press FM01-LC reactor to account for controlling factors of the system. The CFDX removal is improved when HClO predominate in solution due to its higher oxidation potential, co-assisted with the presence of Cl2 (pH = 2), while the CFDX molecule undergoes a slight acid hydrolysis. The contaminant destruction is controlled by the kinetics arising between the active chlorine species adsorbed on the electrode surface (HClOads) and the pollutant, since the increase of flow rate in the reactor does not improve the abatement whatsoever. The total CFDX concentration and its antibiotic activity can be eliminated after 15 min using electro-generated active chlorine at the following operating conditions: 0.05 mol L−1 NaCl, natural pH (5.5), 3 mA cm−2 and 4 L min−1. The energy consumption is considerably influenced by the cell voltage and the presence of active chlorine and H+ concentrations. An important biodegradability degree of the final byproducts is produced by active chlorine species, while only two intermediates of cefadroxil oxidation (CFDX-I-1 and CFDX-I-2) are detected after 2 h of treatment using high-performance liquid chromatography (HPLC).
KW - Active chlorine
KW - Cefadroxil
KW - DSA
KW - Electrochemical oxidation
KW - FM01-LC reactor
UR - http://www.scopus.com/inward/record.url?scp=85072560367&partnerID=8YFLogxK
U2 - 10.1016/j.jece.2019.103173
DO - 10.1016/j.jece.2019.103173
M3 - Artículo
AN - SCOPUS:85072560367
SN - 2213-3437
VL - 7
JO - Journal of Environmental Chemical Engineering
JF - Journal of Environmental Chemical Engineering
IS - 3
M1 - 103173
ER -