TY - JOUR
T1 - Autologous mesenchymal stem cells and cutaneous autograft as a treatment for chronic ulcer secondary to diabetes mellitus 2
AU - Benítez-Arvízu, Gamaliel
AU - Palma-Lara, Ícela
AU - Vazquez-Campos, René
AU - Sesma-Villalpando, Raimundo Alfonso
AU - Parra-Barrera, Alberto
AU - Gutiérrez-Iglesias, Gisela
N1 - Publisher Copyright:
© 2015 Academia Mexicana de Cirugía A.C.
PY - 2015/12
Y1 - 2015/12
N2 - Background: Diabetes mellitus 2 has become a global problem. It is estimated that 15-25% of patients could develop a chronic ulcer in their life, and nearly 33% of direct care costs of the diabetes mellitus 2 is spent on treating these ulcers. Mesenchymal stem cells have emerged as a promising cell source for the treatment of these ulcers. Clinical case: The case is presented of a 67 year-old male with a history of diabetes mellitus, acute myocardial infarction, and chronic ulcer involving right foot and part of his leg. He was treated with mesenchymal stem cell management, resulting in skin graft integration and full coverage of the lesion. Conclusion: The implementation of mesenchymal stem cell techniques for treatment of chronic ulcer is feasible. The impact on the population would lead to a significant improvement in their quality of life and reduce healthcare spending.
AB - Background: Diabetes mellitus 2 has become a global problem. It is estimated that 15-25% of patients could develop a chronic ulcer in their life, and nearly 33% of direct care costs of the diabetes mellitus 2 is spent on treating these ulcers. Mesenchymal stem cells have emerged as a promising cell source for the treatment of these ulcers. Clinical case: The case is presented of a 67 year-old male with a history of diabetes mellitus, acute myocardial infarction, and chronic ulcer involving right foot and part of his leg. He was treated with mesenchymal stem cell management, resulting in skin graft integration and full coverage of the lesion. Conclusion: The implementation of mesenchymal stem cell techniques for treatment of chronic ulcer is feasible. The impact on the population would lead to a significant improvement in their quality of life and reduce healthcare spending.
KW - Chronic ulcer
KW - Mesenchymal stem cells
KW - Type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=84946547047&partnerID=8YFLogxK
U2 - 10.1016/J.CIRCEN.2015.11.010
DO - 10.1016/J.CIRCEN.2015.11.010
M3 - Artículo
C2 - 26164137
SN - 0009-7411
VL - 83
SP - 532
EP - 536
JO - Cirugia y Cirujanos (English Edition)
JF - Cirugia y Cirujanos (English Edition)
IS - 6
ER -