TY - JOUR
T1 - Arabinogalactan-proteins and the research challenges for these enigmatic plant cell surface proteoglycans
AU - Tan, Li
AU - Showalter, Allan M.
AU - Egelund, Jack
AU - Hernandez-Sanchez, Arianna
AU - Doblin, Monika S.
AU - Bacic, Antony
PY - 2012/6/27
Y1 - 2012/6/27
N2 - Arabinogalactan-proteins (AGPs) are complex glycoconjugates that are commonly found at the cell surface and in secretions of plants. Their location and diversity of structures have made them attractive targets as modulators of plant development but definitive proof of their direct role(s) in biological processes remains elusive. Here we overview the current state of knowledge on AGPs, identify key challenges impeding progress in the field and propose approaches using modern bioinformatic, (bio)chemical, cell biological, molecular and genetic techniques that could be applied to redress these gaps in our knowledge.
AB - Arabinogalactan-proteins (AGPs) are complex glycoconjugates that are commonly found at the cell surface and in secretions of plants. Their location and diversity of structures have made them attractive targets as modulators of plant development but definitive proof of their direct role(s) in biological processes remains elusive. Here we overview the current state of knowledge on AGPs, identify key challenges impeding progress in the field and propose approaches using modern bioinformatic, (bio)chemical, cell biological, molecular and genetic techniques that could be applied to redress these gaps in our knowledge.
KW - AGP polysaccharide complexes
KW - Arabinogalactan-proteins
KW - Cell surface signaling
KW - Fasciclin-like AGP
KW - Galactosyltransferase
KW - Glycosylphosphatidylinositol anchor
UR - http://www.scopus.com/inward/record.url?scp=84870199057&partnerID=8YFLogxK
U2 - 10.3389/fpls.2012.00140
DO - 10.3389/fpls.2012.00140
M3 - Artículo de revisión
AN - SCOPUS:84870199057
SN - 1664-462X
VL - 3
JO - Frontiers in Plant Science
JF - Frontiers in Plant Science
IS - JUN
M1 - 140
ER -