TY - JOUR
T1 - Antibody detection tests for Onchocerca volvulus
T2 - Comparison of the sensitivity of a cocktail of recombinant antigens used in the indirect enzyme-linked immunosorbent assay with a rapid-format antibody card test
AU - Rodríguez-Pérez, Mario A.
AU - Domínguez-Vázque, Alfredo
AU - Méndez-Galván, Jorge
AU - Sifuentes-Rincón, Ana M.
AU - Larralde-Coronal, Patricia
AU - Barrera-Saldaña, Hugo A.
AU - Bradley, Janette E.
N1 - Funding Information:
Acknowledgements We thank Consejo Nacional de Ciencia y Tecnologia, Mexico for financial support (grant no. 34486-M), and the Centro de Biotecnologia Gen6mica, Instituto Polit~nico Nacional, Mfixico (grant no. 2002-0001). We also thank Rafael S~nchez and Marco Sandoval from Centro de Investigacion de Paludis-mo, and Dr Jorge Ricfirdez from Laboratorio Estatal de Salud Pflblica, Instituto de Salud de Chiapas, Mexico for assistance with fieldwork. We also thank Olga Real (Universidad Valle del Bravo, Mexico) for her critical reading of the manuscript.
PY - 2003/9
Y1 - 2003/9
N2 - There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasiselimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were compared in a Mexican population with onchocerciasis. The sensitivity of the ELISA and ICT was 97% and 86%, respectively.
AB - There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasiselimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were compared in a Mexican population with onchocerciasis. The sensitivity of the ELISA and ICT was 97% and 86%, respectively.
KW - Detection
KW - Diagnosis
KW - Enzyme-linked immunosorbent assay
KW - Immunochromatographic test
KW - Mexico
KW - Onchocerca volvulus
KW - Onchocerciasis
UR - http://www.scopus.com/inward/record.url?scp=7244224882&partnerID=8YFLogxK
U2 - 10.1016/S0035-9203(03)80018-4
DO - 10.1016/S0035-9203(03)80018-4
M3 - Artículo
SN - 0035-9203
VL - 97
SP - 539
EP - 541
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 5
ER -