Anti-allodynic effect of mangiferin in neuropathic rats: Involvement of nitric oxide-cyclic GMP-ATP sensitive K⁺ channels pathway and serotoninergic system

Química

• Antiallodynic 100%
• Mangiferin 83%
• Intrathecal 44%
• SB 224289 28%
• Serotonin 1D Antagonist 27%
• Serotonin 1B Antagonist 25%
• Methiothepin 23%
• Serotonin 1A Antagonist 21%
• Serotonergic Antagonist 21%
• Nitric Oxide Synthase Inhibitor 19%
• Narcotic Antagonist 19%
• Naloxone 18%
• Antinociceptive 17%
• Agent Interacting With Transmitter, Hormone or Drug Receptor 14%
• Filament 12%

Medicina y ciencias biológicas

• mangiferin 84%
• Cyclic GMP 60%
• Nitric Oxide 42%
• Adenosine Triphosphate 40%
• Serotonin 5-HT1 Receptor Antagonists 20%
• Spinal Nerves 17%
• Hyperalgesia 15%
• Neuralgia 14%
• Ligation 12%
• BRL 15572 9%
• SB 22489G 8%
• Receptor, Serotonin, 5-HT1D 7%
• Methiothepin 7%
• N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide 7%
• serotonin 5 receptor 6%
• Receptor, Serotonin, 5-HT1B 6%
• Serotonin Antagonists 6%
• Guanylate Cyclase 5%
• Receptor, Serotonin, 5-HT1A 5%
• Narcotic Antagonists 5%
• Glyburide 5%
• Serotonin Receptors 5%
• Neurobiology 5%
• NG-Nitroarginine Methyl Ester 5%
• Peripheral Nervous System 5%
• Naloxone 5%
• Nitric Oxide Synthase 4%
• Central Nervous System 3%
• Pain 2%
• Wounds and Injuries 2%