TY - JOUR
T1 - β1 adrenergic receptor polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo populations of Mexico
AU - Fragoso, José Manuel
AU - Rodríguez-Pérez, José Manuel
AU - Pérez-Vielma, Nadia
AU - Martínez-Rodríguez, Nancy
AU - Vargas-Alarcón, Gilberto
PY - 2005/8
Y1 - 2005/8
N2 - The β1 adrenergic receptor genotypes (Ser49Gly and Arg389-Gly) were determined in 190 individuals from 3 Mexican populations. Mestizos and Teenek present the highest frequencies for the *Arg allele and the lowest frequencies for the *Gly allele (Arg389Gly) compared to European, Asian, and African populations. Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations.
AB - The β1 adrenergic receptor genotypes (Ser49Gly and Arg389-Gly) were determined in 190 individuals from 3 Mexican populations. Mestizos and Teenek present the highest frequencies for the *Arg allele and the lowest frequencies for the *Gly allele (Arg389Gly) compared to European, Asian, and African populations. Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations.
KW - Mayos
KW - Mestizos
KW - Mexican populations
KW - Teenek
KW - β adrenergic receptor
UR - http://www.scopus.com/inward/record.url?scp=28844436788&partnerID=8YFLogxK
U2 - 10.1353/hub.2005.0060
DO - 10.1353/hub.2005.0060
M3 - Artículo
SN - 0018-7143
VL - 77
SP - 515
EP - 520
JO - Human Biology
JF - Human Biology
IS - 4
ER -