Versatile β-Lactam Synthons: Enantiospecific Synthesis of (−)-Polyoxamic Acid

Bimal K. Banik; Maghar S. Manhas; Ajay K. Bose

doi:10.1021/jo00054a007

Versatile β-Lactam Synthons: Enantiospecific Synthesis of (−)-Polyoxamic Acid

Bimal K. Banik, Maghar S. Manhas, Ajay K. Bose

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

An optically pure cis-α-hydroxy β-lactam of predictable absolute configuration prepared from readily available d-mannitol has been utilized for the synthesis of the non-natural enantiomer of polyoxamic acid through a series of stereospecific reactions.

Original language	English
Pages (from-to)	307-309
Number of pages	3
Journal	Journal of Organic Chemistry
Volume	58
Issue number	2
DOIs	https://doi.org/10.1021/jo00054a007
State	Published - 1993
Externally published	Yes

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title = "Versatile β-Lactam Synthons: Enantiospecific Synthesis of (−)-Polyoxamic Acid",

abstract = "An optically pure cis-α-hydroxy β-lactam of predictable absolute configuration prepared from readily available d-mannitol has been utilized for the synthesis of the non-natural enantiomer of polyoxamic acid through a series of stereospecific reactions.",

author = "Banik, {Bimal K.} and Manhas, {Maghar S.} and Bose, {Ajay K.}",

year = "1993",

doi = "10.1021/jo00054a007",

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journal = "Journal of Organic Chemistry",

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T1 - Versatile β-Lactam Synthons

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AU - Banik, Bimal K.

AU - Manhas, Maghar S.

AU - Bose, Ajay K.

PY - 1993

Y1 - 1993

N2 - An optically pure cis-α-hydroxy β-lactam of predictable absolute configuration prepared from readily available d-mannitol has been utilized for the synthesis of the non-natural enantiomer of polyoxamic acid through a series of stereospecific reactions.

AB - An optically pure cis-α-hydroxy β-lactam of predictable absolute configuration prepared from readily available d-mannitol has been utilized for the synthesis of the non-natural enantiomer of polyoxamic acid through a series of stereospecific reactions.

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U2 - 10.1021/jo00054a007

DO - 10.1021/jo00054a007

M3 - Artículo

SN - 0022-3263

VL - 58

SP - 307

EP - 309

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 2

ER -

Versatile β-Lactam Synthons: Enantiospecific Synthesis of (−)-Polyoxamic Acid

Abstract

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