Abstract
This paper presents the results of comparative analysis of Raman scattering spectra of CdSe/ZnS QDs covered by polymer with and without bio-conjugation to the mouse anti PSA (Prostate-Specific Antigen) antibodies (mab). Commercial CdSe/ZnS QDs used in the study are characterized by the color emission with the maximum at 565 nm (2.19 eV) at 300 K. Raman scattering spectra measured at room temperature demonstrate two groups of peaks: i) related to the Si substrate at 230-460, 522, 610, 670, 940-1040 cm-1 and 2) to polymer on the QD surface in the spectral range 1268-3310 cm-1. It is revealed that the QD bio-conjugation to the anti PSA mab is accompanied by the variation dramatically in the intensity of Raman lines of both types. The explanation of Raman peak stimulation in bioconjugated QDs has been proposed on the base of surface enhanced Raman scattering (SERS) effect.
| Translated title of the contribution | Variación de espectros Raman de puntos cuánticos CdSe/ZnS en la bioconjugación |
|---|---|
| Original language | English |
| Pages (from-to) | 1192-1195 |
| Number of pages | 4 |
| Journal | Physica Status Solidi (C) Current Topics in Solid State Physics |
| Volume | 7 |
| Issue number | 3-4 |
| DOIs | |
| State | Published - 2010 |
| Event | 23rd International Conference on Amorphous and Nanocrystalline Semiconductors, ICANS23 - Utrecht, Netherlands Duration: 23 Aug 2009 → 28 Aug 2009 |