Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction

Joaquín G. Marrero; Laurence M. Harwood

doi:10.1016/j.tetlet.2009.03.063

Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction

Joaquín G. Marrero, Laurence M. Harwood

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown

Original language	English
Pages (from-to)	3574-3576
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	26
DOIs	https://doi.org/10.1016/j.tetlet.2009.03.063
State	Published - 1 Jul 2009
Externally published	Yes

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10.1016/j.tetlet.2009.03.063

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title = "Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction",

abstract = "We report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown",

author = "Marrero, {Joaqu{\'i}n G.} and Harwood, {Laurence M.}",

note = "Funding Information: We thank S. Mushtaq for technical assistance. J.G.M. is grateful to the Spanish Foundation {\textquoteleft}Alfonso Mart{\'i}n Escudero{\textquoteright} for a Postdoctoral Fellowship. ",

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T1 - Towards the total synthesis of colletofragarones

T2 - constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction

AU - Marrero, Joaquín G.

AU - Harwood, Laurence M.

N1 - Funding Information: We thank S. Mushtaq for technical assistance. J.G.M. is grateful to the Spanish Foundation ‘Alfonso Martín Escudero’ for a Postdoctoral Fellowship.

PY - 2009/7/1

Y1 - 2009/7/1

N2 - We report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown

AB - We report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown

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U2 - 10.1016/j.tetlet.2009.03.063

DO - 10.1016/j.tetlet.2009.03.063

M3 - Artículo

SN - 0040-4039

VL - 50

SP - 3574

EP - 3576

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 26

ER -

Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction

Abstract

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