The reaction of spiroepoxycyclohexadienones towards cyanide nucleophiles

Rubén Córdoba, Aurelio G. Csákÿ, Joaquín Plumet, Fernando López Ortiz, Rafael Herrera, Hugo A. Jiménez-Vázquez, Joaquín Tamariz

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The reaction of spiroepoxycyclohexadienones 1 with TMSCN in the presence of catalytic amounts of Bu4NCN results in the formation of two diastereomeric cyanohydrins. Alternatively, the reaction of 1 with equimolecular amounts of Bu4NCN gave rise to products arising from two other different reaction paths.

Original languageEnglish
Pages (from-to)3825-3830
Number of pages6
JournalTetrahedron
Volume60
Issue number17
DOIs
StatePublished - 19 Apr 2004

Keywords

  • Catalysis
  • Cyanides
  • Epoxides

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